Ludwig’s angina is a rapidly progressive, potentially life-threatening infection of the floor of the mouth that can lead to airway compromise. We report the case of a 56-year-old man with chronic kidney disease on regular haemodialysis who presented with progressive submandibular swelling, trismus, and dysphagia following an untreated odontogenic infection. Initial management included airway monitoring and broad-spectrum intravenous antibiotics. Clinical deterioration occurred on the third day, with worsening respiratory symptoms and reduced mouth opening. Neck ultrasonography revealed a loculated abscess extending from the right upper jugular to the submandibular region with diffuse subcutaneous oedema. The patient subsequently underwent surgical decompression and incision drainage, yielding purulent material for culture. Antimicrobial therapy was continued based on susceptibility results, resulting in satisfactory clinical improvement and wound healing. This case highlights the importance of early recognition, vigilant airway assessment, prompt imaging, and timely surgical intervention in the management of Ludwig’s angina, particularly in patients with predisposing comorbidities.
Keywords: Ludwig’s angina; Odontogenic infection; Airway management; Chronic disease Knowledge
How to cite this article:Mahmudah I, Rizkiawan N, Hadi U.; Ludwig’s Angina with Evolving Airway Compromise in a Patient with Chronic Kidney Disease: A Case Report..Int J Drug Deliv Technol. 2026;16(1s): 678-682; DOI: 10.25258/ijddt.16. 678-682