1Department of General Medicine, Sree Balaji Medical College, Tamil Nadu. Mail Id: drveeravignesh@gmail.com. ORCID ID: 0009-0000-3437-1457
2Professor, General Medicine, Sree Balaji Medical College, India. Mail Id: drpadmaramesh86@gmail.com. ORCID ID: 0000-0002-9938-6462
3Department of General Medicine, Sree Balaji Medical College, Tamil Nadu. Mail Id: turpusharath@gmail.com. ORCID ID: 0009-0001-6314-367X
4Department of General Medicine, Sree Balaji Medical College, Tamil Nadu. Mail Id: m.bhavanareddy12@gmail.com
Isoniazid (INH), a cornerstone of anti-tubercular therapy (ATT), is well-tolerated but can cause significant toxicity, including hepatotoxicity and neurotoxicity, in a subset of patients. This case report describes a 46-year-old male with abdominal cocoon syndrome secondary to tuberculous peritonitis who developed isoniazid toxicity during the course of treatment. The report outlines the clinical presentation, diagnostic workup, and management of both the underlying condition and the drug-induced toxicity.
Keywords: Tuberculosis, Isoniazid, Hepatotoxicity, Neurotoxicity, Abdominal Tuberculosis
How to cite this article: VeeraVignesh V, Padma V, Turpu SCR, Reddy B. Case Report on Isoniazid Toxicity in a 46-Year-Old Male with Abdominal Cocoon Syndrome and Tuberculous Peritonitis. Int J Drug Deliv Technol. 2026;16(2): 83-86; DOI: 10.25258/ijddt.16.2.11
Source of support: Nil.
Conflict of interest: None