1,2,3,4Department of Neurology, Diponegoro University / Dr. Kariadi Hospital Semarang – Indonesia. Email: retnaku_icu@yahoo.com. ORCID: 0000-0003-1072-6123; bariscatur@yahoo.com. ORCID: 0000-0001-8492-2018; gerardjuswanto@gmail.com. ORCID: 0009-0000-4340-0301; hayuningtyas.dian@gmail.com. ORCID: 0009-0007-0094-3454
5Ruten Inc. Email: kazutaka@ruten-neuro.com. ORCID: 0000-0001-7679-0430
Received: 19th Oct, 2025; Revised: 29th Dec, 2025; Accepted: 22nd Jan, 2026; Available Online: 13th Feb, 2026
Background: Neurocritical patients often present with complex neurological conditions requiring continuous monitoring and rapid intervention to prevent secondary brain injury. Clinical and Imaging assessments might fail to detect evolving cerebral dysfunction in real time. Quantitative EEG (QEEG) offers transformative approach by providing objective, real time metrics for cerebral monitoring to identify subclinical seizures and predicting patients outcomes.[1]
Methods: A Cross-sectional design including 30 patients with Encephalopathy who met the inclusion criteria such as Post ROSC, Meningoencephalitis, Non-Hemorrhagic Stroke and Uremic Encephalopathy.
Results: Descriptive analysis revealed that 70% of the total samples showed a decrement in Beta Absolute Power. In The Group Post ROSC 25% of total samples showed Burst suppression. Hypocoherence Pattern were found in the Group Post ROSC and Meningoencephalitis 75% and 80% respectively. Asymmetry Amplitude was found in all Non-Hemorrhagic Stroke group.
Discussion: This study demonstrates pattern of QEEG in Critical Care Unit patients with Encephalopathy. Low Beta absolute power may indicate cortical dysfunction in patients with altered mental status regardless of the etiology.[2] As Diffuse injury existed, it induced neural disruptions that may be found in hypocoherence pattern of QEEG that may lead to cognitive impairment in the future. [3] Burst suppression in the background pattern was associated with poor outcome, in this research it was found in Post ROSC group. [4] The asymmetry amplitude could indicate lateralization as most of these patterns found in Non-Hemorrhagic Stroke.[5]
Keywords: Quantitative Electroencephalography, Post ROSC, Encephalopathy, Neurocritical.
How to cite this article: Retnaningsih, Bintoro AC, Jusswanto G, Hayuningtyas D, Takahashi K. The Role of Quantitative Electroencephalography in Neurocritical Care: A Cross Sectional Study. Int J Drug Deliv Technol. 2026;16(2): 14-18. DOI: 10.25258/ijddt.16.2.3
Source of support: None.
Conflict of interest: None