1Professor and HOD, PhD Scholar, Department of Community Medicine, Dr D.Y. Patil Homoeopathic Medical College & Research Centre, Dr D.Y. Patil Vidyapeeth, (Deemed to be University), Pimpri, Pune, Maharashtra, India. Email: deepali.ingle@dpu.edu.in
2*Corresponding Author - Professor and HOD, PhD Scholar, Department of Gynaecology and Obstetrics, Dr D.Y. Patil Homoeopathic Medical College & Research Centre, Dr D.Y. Patil Vidyapeeth, (Deemed to be University), Pimpri, Pune, Maharashtra, India. Email: sonali.dalvi@dpu.edu.in. ORCID ID: 0000-0003-1304-7994
Background: Fatigue, weight gain, and sadness are just a few of the symptoms of hypothyroidism, a common endocrine condition that significantly affects the quality of life (QoL) of patients. Although homoeopathic medicines have been suggested as a supplemental or alternative therapy to conventional therapies, it is still unclear how successful they are.
Objective: To methodically assess the efficacy of homeopathic remedies in managing symptoms and improving Quality of life in individuals who have been diagnosed with hypothyroidism.
Methods: An extensive evaluation was carried out of observational studies, case series, and randomised controlled trials (RCTs). From the beginning until November 2024, searches were conducted using internet resources including the Cochrane Library, PubMed, Embase, and Scopus. Studies were included if they assessed the impact of homeopathic remedies on symptom management or QoL in hypothyroidism patients. Using predefined tools such as the GRADE, the Cochrane Risk of Bias Tool, and the technique, data extraction and the standard assessment were conducted.
Results: Out of 1,500 identified records, Twelve studies satisfied the requirements for inclusion, including 8 RCTs, 2 cohort studies, and 2 case series. The included studies involved a total of 1,200 participants with primary hypothyroidism. Key findings indicated that certain homeopathic remedies, such as Calcarea carbonica and Natrum muriaticum, demonstrated modest improvements in fatigue and mental health scores compared to placebo or standard care. However, the evidence for their effectiveness in improving biochemical parameters (e.g., TSH levels) was inconsistent. QoL measures showed marginal improvement, with most studies reporting positive effects on physical and psychological domains. There was substantial variation in research design, interventions, and results, the evidence's overall quality ranged from low to moderate.
Conclusion: Homeopathic remedies may provide symptomatic relief and slight improvements in QoL for patients with hypothyroidism. However, due to methodological limitations and the lack of consistent Evidence calls for further high-quality randomized controlled trials to confirm these results.
Keywords: Homeopathy, hypothyroidism, quality of life, symptom management, alternative medicine, systematic review.
How to cite this article: Ingle D, Dalvi S. Effectiveness of homeopathic remedies in managing symptoms and improving quality of life for patients diagnosed with hypothyroidism: A Systematic Review. Int J Drug Deliv Technol. 2026;16(2): 808-818. DOI: 10.25258/ijddt.16.1.87
Source of support: Nil.
Conflict of interest: None