International Journal of Drug Delivery Technology
Volume 16, Issue 2, 2026

Phytochemical Analysis and Evaluation of Antimicrobial Activity of Ethanolic Flower Extract of Clitoria Ternatea

1* Gunturu Jaya Syamala, 2 Gunturu Uma Soundarya, 3 Penumala Bhagya Rekha, 4 G. Durga Devi, 5 Kanakala Saraswati, 6 Vepuri Bindu Madhuri

1*Assistant Professor, NRI College of Pharmacy, Pothavarappadu Village, Agiripalli Mandal, Eluru District -521211, Andhra Pradesh. Email: akshayajayasyamala@gmail.com. Orcid Id: 0009-0003-4835-6823

2Assistant Professor, NIMRA College of Pharmacy, Jupudi, Ibrahimpatnam, NTR District -521456, Andhra Pradesh. Orcid Id: 0009-0007-3786-8494

3Assistant Professor, V.V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh.

4Associate Professor, NRI College of Pharmacy, Pothavarappadu Village, Agiripalli Mandal, Eluru District -521211, Andhra Pradesh. Orcid ID: 0009-0003-2305-7835

5Assistant Professor, NRI College of Pharmacy, Pothavarappadu Village, Agiripalli Mandal, Eluru District -521211, Andhra Pradesh. Orcid ID: 0009-0006-0563-8240

6Associate Professor, NRI College of Pharmacy, Pothavarappadu Village, Agiripalli Mandal, Eluru District -521211, Andhra Pradesh. Orcid Id: 0009-0005-7340-5062


ABSTRACT

The Clitoria ternatea plant, commonly known as Butterfly Pea, is a valuable source of bioactive compounds with numerous therapeutic benefits. This study aimed to investigate the phytochemical profile and antimicrobial potential of the ethanolic flower extract of Clitoria ternatea. The extraction process was conducted using ethanol, followed by phytochemical screening and analysis using Liquid Chromatography-Mass Spectrometry (LC-MS). The identified phytoconstituents include flavonoids, anthocyanins, alkaloids, and phenolic compounds, which are known for their antioxidant, anti-inflammatory, and antimicrobial properties. The antimicrobial activity was assessed against various bacterial and fungal strains using the cup plate method, demonstrating significant inhibition at concentrations of 15, 30, and 45 mg/ml. The study highlights the potential of Clitoria ternatea as a source of natural antimicrobial agents and its therapeutic relevance in treating infectious diseases. Further research is necessary to explore the specific compounds responsible for these effects and their mechanisms of action.

Keywords: Clitoria ternatea, Ethanolic Extract, Phytochemical Analysis, LC-MS, Antimicrobial Activity, Flavonoids, Anthocyanins, Alkaloids, Antioxidant Properties, Antibacterial, Fungal Inhibition, Medicinal Plants, Natural Products

How to cite this article: Syamala GJ, Soundarya GU, Rekha PB, Devi GD, Saraswati K, Madhuri VB. Phytochemical Analysis and Evaluation of Antimicrobial Activity of Ethanolic Flower Extract of Clitoria Ternatea. Int J Drug Deliv Technol. 2026;16(2): 73-79; DOI: 10.25258/ijddt.16.2.9

Source of support: Nil.

Conflict of interest: None