The study aims to synthesize Vitis vinifera peel gold nanoparticles (VvAuNPs). an eco-friendly green synthesis and with precise biological activities. Its assessment focuses on the antimicrobial, antioxidant and its potential to show ant diabetic property of AuNPs. In this study it is revealed that we use to evaluate the biological and green synthesis of gold nana particle the (AuNPs) derived from Vitis vinifera peel extract. The phytometabolites present in the peel extract acts as a natural reducing and stabilizing agent during synthesis. VvAuNPs structural prediction were conformed with spectral studies. Antibacterial assay revealed significant (zone of inhibitions) against Staphylococcus aureus, Bacillus subtilis and Escherichia coli, pseudomonas aeruginosa bacterial strains, indicating strong bactericidal efficiency. The polyphenolic activity is determined through DPPH and FRAP radical scavenging assays, exhibited excellent free radical neutralization capacity. Antidiabetic activity assessed via α-amylase and α-glucosidase inhibition demonstrated effective enzyme suppression, suggesting glucose-regulating potential. Moreover, anti-inflammatory studies based on protein denaturation and membrane stabilization assays confirmed substantial inhibition of inflammatory mediators.
Keywords: Vitis vinifera peel; gold nanoparticles; green synthesis; antibacterial; antioxidant; antidiabetic; Activity.
How to cite this article: Ruqiah SK, Azeem MU, Evaluation of Biological Activities of Gold Nanoparticles Derived from Vitis vinifera Peel Extract. Int J Drug Deliv Technol. 2026;16(2s): 148-159; DOI: 10.25258/ijddt.16.148-159