International Journal of Drug Delivery Technology
Volume 16, Issue 2s

Comparative Evaluation of Postoperative Pain Following Single Visit and Multiple - Visit Root Canal Treatment: A Randomized Clinical Trial

Santa Kalita1, Sibani Sarangi2, Kiran Panzade3, Netra Shah4, Athira M5, Vikram Karande6, Ritik Kashwani7

1Post graduate Trainee, Department of Conservative Dentistry & Endodontics, Kalinga Institute of Dental Sciences, Bhubaneswar, India
2Senior Lecturer, Department of Periodontology, Hitech Dental College and Hospital, Bhubaneswar, India
3MDS, Conservative Dentistry and Endodontics from Government Dental College and Hospital, Mumbai, Maharashtra, India
4Department of Prosthodontics, Crown & Bridge and Oral Implantology, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune 411018, Maharashtra, India
5MDS (Prosthodontics), Assistant Professor, Department of Prosthodontics, Educare institute of Dental Sciences, Chattiparamba, Malappuram, Kerala, India
6Professor & HOD, Department of Oral & Maxillofacial Surgery, D.Y. Patil Dental School, Lohegaon, Pune, Maharashtra, India
7Department of Oral Medicine and Radiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India

ABSTRACT

Background: Pain after the root canal is a common issue after the procedure and can have a negative impact on the comfort and satisfaction of patients. The recent developments on endodontics procedures and materials have ignited the increasing popularity of the single-visit root canal treatment as an alternative to the traditional multi-visit root canal treatment. However, there has been a continuous debate on whether the effect of the number of treatment visits on the postoperative pain is significant.

Aim: The aim of this randomized controlled trial was to comparatively determine postoperative pain with a single-visit root canal treatment and multiple-visit root canal treatment.

Materials and Methods: This was a prospective, randomized, controlled clinical trial that involved 200 participants that needed primary endodontic therapy. They were randomly selected into one of two groups; Group I (single visit root-canal treatment, n=100) and Group II (multiple visit root-canal treatment, n=100). The instruments were used in all the procedures and irrigation was done according to standardized procedures. The Quantification of post-operative nociception was measured on the Visual Analog Scale (VAS) at 6, 24, 48, and 7 days and analgesic intake was monitored. The statistical analyses were conducted using STATA software and a p-value below 0.05 was taken to be considered as statistically significant.

Results: The two groups had an increasing reduction of the postoperative pain. Group I showed a much lower mean score on Visual Analog Scale (VAS) at 24 has and 48 has compared with Group II (p < 0.05). There was no statistically significant difference at 6 hours and at 7 days. The degree of consumption of analgesics was very high in the multiple-visit group.

Conclusion: Single-visit root-canal therapy was linked to lower levels of postoperative pain and lower levels of analgesic usage as compared to multi-visit treatment particularly at the initial stages of the postoperative phase.

Keywords: Multiple-visit root canal treatment, Postoperative pain, Randomized clinical trial, Root canal treatment, Single-visit root canal treatment

How to cite this article: Kalita S, Sarangi S, Panzade K, Shah N, Athira M, Karande V, Kashwani R, Comparative Evaluation of Postoperative Pain Following Single Visit and Multiple - Visit Root Canal Treatment: A Randomized Clinical Trial. Int J Drug Deliv Technol. 2026;16(2s): 645-650; DOI: 10.25258/ijddt.16.645-650