International Journal of Drug Delivery Technology
Volume 16, Issue 2s

Impact of Plasma Uric Acid and Albumin Levels with Severity of Parkinson's Disease in a Tertiary Coastal Hospital: An Observational study

Dr. Prabakaran Vaithinathan1*, Dr. Nitesh Bholanath Yadav2, Dr. Sakthivel Vaithiyanathan3, Dr. C. Ganesan4

1*Assistant Professor, Department of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, Puducherry, India
2Post graduate, Department of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, Puducherry, India
3Professor and Head of the Department, Department of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, Puducherry, India
4Professor, Department of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, Puducherry, India

ABSTRACT

In recent years impact of Plasma Uric acid and albumin with the Severity of Parkinson's Disease has been studied but no Study has been done in this remote Coastal region of India. To find if plasma uric acid and albumin are independent risk factors for the progression of the severity of Parkinson's Disease in the coastal area of Karaikal. A total of 44 cases over 14 months were recruited at Department of General Medicine, Vinayaka Mission's Medical college & Hospital, Karaikal. General data including age, sex, severity by Hoehn and Yahr Scale (H&Y scale) and Webster rating scale (WRS), Plasma uric acid and Albumin levels were accessed. As the Severity of Parkinson's Disease Increased the Plasma levels of uric acid and albumin were significantly decreasing. The P-value of serum Uric acid and Albumin with H&Y scale is <0.001 and with WRS is <0.001 which is statistically significant. Both plasma Uric acid and Albumin can be considered independent risk factor for Parkinson's Disease in the coastal region of Karaikal.

Keywords: Parkinson's disease, Serum Uric Acid, Serum Albumin, Interaction, Oxidative stress, Pathophysiology of Parkinson's.

How to cite this article: Vaithinathan P, Yadav NB, Vaithiyanathan S, Ganesan C, Impact of Plasma Uric Acid and Albumin Levels with Severity of Parkinson's Disease in a Tertiary Coastal Hospital: An Observational study. Int J Drug Deliv Technol. 2026;16(2s): 719-723; DOI: 10.25258/ijddt.16.719-723