1Post Graduate, Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. Email: smdivyashree94@gmail.com
2,3Professor, Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. Email: shobdr@gmail.com, srismitha.s@gmail.com
Background: Skin adnexal tumors (SATs) are rare growths that come from the skin's pilosebaceous and sweat gland structures. Their various forms and similarities to other skin lesions make clinical diagnosis tricky. Therefore, histopathology is crucial for accurate identification and prognosis.
Aim: This study aims to examine the clinicopathological features, anatomical distribution, and differentiation lineage of rare skin adnexal tumors at a tertiary care hospital.
Methods: A retrospective study included 42 histopathologically confirmed SAT cases diagnosed between 2022 and 2024. We evaluated tumors for demographic features, anatomical location, histological subtype, and classified them as benign or malignant.
Results: Follicular tumors were the most common at 42.9%, followed by sweat gland tumors at 40.5% and sebaceous tumors at 11.9%. Pilomatricoma was the most frequent benign lesion at 33.3%. Rare malignant tumors included adenoid cystic carcinoma, eccrine mucinous carcinoma, and high-grade malignant trichilemmal tumor. Malignancies accounted for 7.1% of the cases.
Keywords: NA
How to cite this article: Sathiya Murthy D, Shobana B, Srismitha S. Dermal Adnexal Neoplasms: Exploring Rare Variants and Their Clinical Behavior. Int J Drug Deliv Technol. 2026;16(3): 324-339. DOI: 10.25258/ijddt.16.3.37
Source of support: Nil.
Conflict of interest: None