International Journal of Drug Delivery Technology
Volume 16, Issue 3, 2026

Phytochemical Screening and Anti TB Activity of stems of Portulaca Grandiflora Hook

Aasha Rathod1, Dr. R.D Ingole2, Shaikh Bilal S.S3*, Dr. Seema Pattewar4, Dr. Deepak Patil5, Dr. Neha Kajale6, Dr. Prashali Gorakh Shinde7, Nikita Kishor Kale8, Vasudha Swapnil Bavadekar9, Gonge Omkar Abasaheb10

1M.Pharm Student, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra, India

2Principal, DJPS College of Pharmacy Pathri, Dist. Parbhani, Maharashtra, India

3,10Lecturer, DJPS College of Pharmacy Pathri, Dist. Parbhani, Maharashtra, India

4In-charge Principal, Suryadatta College of Pharmacy Healthcare and Research, Bavdhan-Pune, Maharashtra, India

5Principal, Dr. Kolpe Institute of Pharmacy, Kolpewadi, Kopargaon, Maharashtra, India

6Principal, SVS College of Pharmaceutical Education and Research, Tembhurni, Solapur, Maharashtra, India

7Associate Professor, Late Laxmibai Phadtare College of Pharmacy – Kalamb, Maharashtra, India

8,9PES Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India

* Corresponding author: Shaikh Bilal S.S, Email: sbilal8856@gmail.com
Received: 13th Dec, 2025; Revised: 7th Feb 2026; Accepted: 10th Feb, 2026; Available Online: 30th March, 2026

ABSTRACT

This article focuses on the use of herbal medicine, rooted in pharmacognosy, and the therapeutic application of medicinal plants, commonly known as herbalism, phytomedicine, or phytotherapy. It delves into the potential of Portulaca grandiflora Hook in combating tuberculosis (TB), a disease with ancient origins. The focus is on the anti-tubercular properties of Portulaca grandiflora Hook. The study involves the two-extraction method. Using the two extracts (ethanol and aqueous extract) isolating the various phytochemical compounds such as flavonoids, alkaloids, tannins, carbohydrates, saponins, and steroids from this plant. These compounds are identified using Thin Layer Chromatography (TLC). Furthermore, the isolated compounds undergo thorough characterization through techniques including UV spectroscopy and infrared spectroscopy (IR) shedding light on their potential effectiveness against TB. The quercetin was found in this study. Docking study was carried using 2FK8 PDB ID.

Keywords: Portulaca grandiflora, physicochemical analysis, Anti tuberculosis activity, Flavonoid compound, docking study of anti TB.

How to cite this article: Rathod A, Ingole RD, Shaikh BSS, Pattewar S, Patil D, Kajale N, Shinde PG, Kale NK, Bavadekar VS, Gonge OA. Phytochemical Screening and Anti TB Activity of stems of Portulaca Grandiflora Hook. Int J Drug Deliv Technol. 2026;16(3): 22-27. DOI: 10.25258/ijddt.16.3.4

Source of support: Nil.

Conflict of interest: None