1*MBBS, MD Assistant Professor, Department of Medicine, Patna Medical College, Patna. Email: dr.sanjay99@yahoo.co.in ORCID: 0009-0000-3262-1870 (Corresponding Author)
2MBBS, Junior Resident, Department of Medicine, Patna Medical College, Patna. Email: snehilsaurabh19@gmail.com ORCID: 0009-0001-2971-5304
3MBBS, Junior Resident, Department of Medicine, Patna Medical College, Patna. Email: skatyayane24@gmail.com ORCID: 0009-0005-0867-4020
Received: 12th Dec, 2025; Revised: 12th Feb 2026; Accepted: 13th Feb, 2026; Available Online: 10th March, 2026
Background: Chronic anemia induces adaptive cardiovascular responses that may eventually lead to structural cardiac changes, including left ventricular hypertrophy (LVH), a known predictor of adverse cardiovascular outcomes¹⁻³.
Objective: To determine the prevalence of LVH in patients with chronic anemia and to evaluate its association with the severity and duration of anemia.
Methods: This cross-sectional study included 120 adult patients with confirmed chronic anemia. Clinical profiles, laboratory findings, and echocardiographic parameters were assessed. LVH was defined based on left ventricular mass index (LVMI)⁹¹⁰.
Results: LVH was present in 52.5% of participants (n=63). The prevalence increased with anemia severity: 20% in mild cases, 48% in moderate cases, and 75% in severe anemia (p<0.001). Mean LVMI values were significantly higher in severe anemia compared to moderate and mild anemia.
Conclusion: LVH is a common finding in chronic anemia and is strongly influenced by both disease severity and duration. Early diagnosis and management of anemia may help prevent adverse cardiac remodeling⁶⁻⁸.
Keywords: Chronic anemia, Left ventricular hypertrophy, Cardiac remodeling, Echocardiography
How to cite this article: Kumar S, Saurabh S, Katyayane S. Burden and Clinical Correlates of Left Ventricular Hypertrophy in Chronic Anemia: A Cross-Sectional Study. Int J Drug Deliv Technol. 2026;16(3): 657. DOI: 10.25258/ijddt.16.3.72
Source of support: Nil.
Conflict of interest: None