A 31-year-old patient presented with symptoms suggestive of hypothyroidism, including heaviness in the abdomen and whole body, constant fatigue, constipation, and increasing body weight. The patient was managed using a single Ayurvedic formulation containing Ashwagandha, Triphala, Shilajit, Guggul, and Kanchanar along with a recommended Pathya-Apathya regimen as mentioned in Bhaishajya Ratnawali Agnimandhya Rogadhikara. The treatment plan was based on Agni Deepana, Ama Pachana, Kapha-Medohara, Rasayana, and Srotoshodhana (especially Rasavaha Strotas) principles. Clinical assessment and serum TSH levels were monitored over a period of two months.
Following the treatment plan, the patient showed symptomatic improvement, particularly in heaviness in the abdomen, energy levels, and digestive regularity. A noticeable reduction in serum TSH levels was noted, although values remained slightly elevated at the end of the observation period. No adverse effects were reported.
The observed clinical and biochemical changes suggest a potentially supportive role of Ayurvedic intervention in managing conditions correlated with hypothyroidism. However, as this is a single case observation, larger controlled studies are required to validate these findings and evaluate repeatability.
Keywords: Hypothyroidism, Agnimandya, Kapha-Medas vriddhi, Ayurveda, TSH, Rasayana therapy.
How to cite this article: Gupta A, Shukla S, Chandrakar R, Sao R. Understanding hypothyroidism as a manifestation of Mandagni: evidence from a case study. Int J Drug Deliv Technol. 2026;16(3s): 942-950; DOI: 10.25258/ijddt.16.3s.114
Source of support: Nil.
Conflict of interest: None