International Journal of Drug Delivery Technology
Volume 16, Issue 3s, 2026

Breast Composition of Contralateral Ultrasonography Grey Scale Characteristics and Breast Mammographic Findings in Breast Cancer Patients

Febie Irsandy Syahruddin 1,2*, Prihantono 3, Muhammad Ilyas 4, Mirna Muis 4, Lina Choridah 5, Rina Masadah 6, Irfan Idris 7, Andi Alfian Zainuddin 8

1Doctoral Program Student, Faculty of Medicine, Hasanuddin University, Hasanuddin Hospital, Makassar, Indonesia.
2Department of Radiology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia.

3Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

4Department of Radiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

5Department of Radiology, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Yogyakarta, Indonesia.

6Department of Pathology Anatomy, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

7Department of Physiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

8Department of Public Health and Community Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

*Corresponding Author: Febie Irsandy Syahruddin, Doctoral Program Student, Faculty of Medicine, Hasanuddin University / Department of Radiology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia.


ABSTRACT

Background: Breast imaging plays a crucial role in the diagnosis and comprehensive assessment of breast cancer. Grey scale ultrasonography and mammography provide complementary information regarding breast tissue characteristics, while evaluation of the contralateral breast is essential to detect occult abnormalities. Understanding the association between imaging findings and demographic or reproductive factors may enhance diagnostic interpretation and patient management.

Methods: This analytic observational study employed a cross-sectional design and was conducted at the Department of Radiology, Universitas Hasanuddin Hospital, Makassar, Indonesia, starting from October 2024 until the required sample size was achieved. A total of 60 breast cancer patients who underwent grey scale breast ultrasonography and contralateral breast mammography were included. Demographic, reproductive, and clinical data were collected from medical records. Imaging findings were classified according to tissue type.

Results: Type C breast tissue was the most predominant pattern observed on both ultrasonography and mammography. No significant associations were found between age, age at menarche, body mass index, parity, menopausal status, or contraceptive use and imaging tissue types (p>0.05). Breastfeeding history showed a significant association with both ultrasonographic tissue type (p=0.021) and mammographic tissue type (p=0.011). Several variables demonstrated trends toward association with imaging patterns, although these did not reach statistical significance.

Conclusion: Grey scale ultrasonography and contralateral breast mammography reveal heterogeneous breast tissue characteristics in breast cancer patients. Breastfeeding history appears to significantly influence breast tissue patterns, emphasizing the importance of incorporating reproductive history into imaging interpretation and comprehensive breast cancer assessment.

Keywords: Breast cancer, Ultrasonography, Mammography, Breast tissue type, Breastfeeding history.

How to cite this article: Syahruddin FI, Prihantono, Ilyas M, Muis M, Choridah L, Masadah R, Idris I, Zainuddin AA. Breast composition of contralateral ultrasonography grey scale characteristics and breast mammographic findings in breast cancer patients. Int J Drug Deliv Technol. 2026;16(3s): 1052-1060; DOI: 10.25258/ijddt.16.3s.126

Source of support: Nil.

Conflict of interest: None