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Green synthesis of metal nanoparticles has emerged as an environmentally benign and sustainable alternative to conventional physical and chemical methods. In the present study, silver nanoparticles (AgNPs) were successfully synthesized using an aqueous leaf extract of Azadirachta indica A. Juss. (Neem) as a natural reducing and stabilizing agent. Neem leaves are rich in bioactive phytochemicals such as flavonoids, phenolics, terpenoids, and proteins, which facilitate nanoparticle formation without the use of toxic chemicals. The synthesis process was confirmed by a visible color change and UV–Visible spectroscopic analysis. Comprehensive characterization of the synthesized AgNPs was carried out using Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Dynamic Light Scattering (DLS), zeta potential analysis, Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray (EDX) spectroscopy. The nanoparticles were found to be spherical, crystalline, nanosized, and stable. The study demonstrates that Azadirachta indica–mediated green synthesis is a simple, cost-effective, and eco-friendly approach with significant potential for pharmaceutical and biomedical applications...
Keywords: Green synthesis; Silver nanoparticles; Azadirachta indica; Neem leaf extract; Nanoparticle characterization; Sustainable nanotechnology
How to cite this article: Sujatha P, Raslamol K, Radha K, Sahni S, Singh C, Deva V, K A, Tiwari G, Raman SG, Green Synthesis and Characterization of Silver Nanoparticles Using Azadirachta indica A. leaf Extracts. Int J Drug Deliv Technol. 2026;16(3s): 193-201; DOI: 10.25258/ijddt.16.3s.27