Volume 16, Issue 3s
Effect of Panchagavya Ghrita Matrabasti on Cognitive Functions in Children with ADHD A Randomised Clinical Study
Dr. Puja CN Pathak 1*, Dr. Durga Prasad Dash 2, Dr. Shakti Singh 3
1*PhD Scholar, Dept of Kaumarabhritya, Sri Sri College of Ayurvedic Science and Research Hospital, Sri Sri University, Cuttack, Odisha; Assistant Professor, Dept. of Kaumarabhritya, Shri Ramchandra Vaidya Ayurvedic Medical College, Lucknow, Uttar Pradesh, India
2Professor & HOD, Dept of Kaumarabhritya, Sri Sri College of Ayurvedic Science and Research Hospital, Sri Sri University, Cuttack, Odisha, India
3Asso. Prof & HOD, Dept of Shalyatantra, SRVAMCH, Lucknow, Uttar Pradesh, India
Author information
1*Email: dr.pujapathak19@gmail.com
ORCID ID: 0000-0002-3590-2835
2Email: durga.d@srisriuniversity.edu.in
ORCID ID: 0000-0002-5291-2154
ABSTRACT
Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder affecting children, characterized by inattention, hyperactivity, and impulsivity. Current pharmacological interventions have significant adverse effects, necessitating exploration of safer Ayurvedic alternatives. To evaluate the efficacy of Panchagavya Ghrita Matra Basti along with Shiroabhyanga in managing ADHD symptoms and compare it with oral administration of Panchagavya Ghrita. A randomized comparative clinical trial was conducted on 100 children aged 6-12 years diagnosed with ADHD using DSM-V criteria. Participants were randomly allocated into two groups: Group A (n=50) received Panchagavya Ghrita Matra Basti (transrectal) with Brahmi Taila Shiroabhyanga for 60 days; Group B (n=50) received oral Panchagavya Ghrita with Brahmi Taila Shiroabhyanga for 60 days. Assessments were conducted at baseline, 30th, 60th, and 90th day using Vanderbilt ADHD Diagnostic Parent Rating Scale and PedsQL. Statistical analysis employed Friedman test for within-group and Mann-Whitney U test for between-group comparisons. Both groups showed significant improvement in ADHD symptoms (p<0.001). Group A demonstrated superior reduction in Predominantly Hyperactive/Impulsive subtype scores at 90th day (Mean difference: 3.62, p<0.001) compared to Group B (Mean difference: 3.84, p<0.001). Total Positive Symptom Score in Inattentive subtype showed significant between-group difference favoring Group A at 90th day (p<0.001). Physical, emotional, social, and school functioning improved significantly in both groups (p<0.001), with Group A showing better school functioning at 90th day (p=0.041). Panchagavya Ghrita Matra Basti with Shiroabhyanga is an effective and safe therapeutic option for managing ADHD in children, with superior outcomes in hyperactive/impulsive symptoms compared to oral administration.
Keywords: ADHD, Panchagavya Ghrita, Matra Basti, Shiroabhyanga, Cognitive functions, Ayurveda
How to cite this article: Pathak PCN, Dash DP, Singh S., Effect of Panchagavya Ghrita Matrabasti on Cognitive Functions in Children with ADHD A Randomised Clinical Study. Int J Drug Deliv Technol. 2026;16(3s): 330-337; DOI: 10.25258/ijddt.16.3s.42