Background: The Autonomic Nervous System regulates energy Homeostasis which is the imbalance between energy intake and expenditure that typically leads to obesity. Hemodynamic and metabolic changes are the outcome of complex interactions between genetic, physiological, behavioral, neurological and metabolic factors. Even among young adults who are generally thought to be healthy, obesity is becoming more common due to shifting lifestyle patterns and stress related behaviors that subtly impair their cardiovascular system and physical fitness level. Cardiovascular disease is more common in obese individuals, which is thought to be caused by autonomic dysfunction and/or metabolic disorders. Heart rate variability (HRV) indications, a diagnostic tool for cardiac autonomic disorders, are affected by changes in cardiac autonomic processes. High-intensity interval training has been widely studied, there is a lack of research on integrated intensive exercise approaches. This study evaluates the clinical efficacy of an Integrated Intensive Exercise Protocol (IIEP) in improving Autonomic Function and Fitness level among Young Obese adults.
Methods: An experimental study was conducted in 50 young obese Adults (BMI 30–39.9 kg/m², aged 18–35), randomly assigned to two groups. Group A (control) followed a prescribed diet and engaged in brisk walking (30 minutes, twice daily, 3 days per week) for 8 weeks. Group B (intervention) underwent IIEP, incorporating aerobic exercise, resistance training, and recreational activities, for 3 days per week over 8 weeks. Subjects of both the groups were assessed at baseline, at the end of 4th week and at the end of 8th week for Heart Rate Variability, and physical fitness level.
Results: The findings of this study provide strong evidence supporting the benefits of an eight-week Integrated Intensive Exercise Protocol (IIEP) in all the measures of HRV (SDNN, RMSDD and PNN50) in the young obese adults. The intervention was found to be safe, feasible, and effective in enhancing the level of physical fitness, increasing the HRV. The intervention group demonstrated significant improvements in HRV indices and physical fitness level compared with the control group. Both groups showed similar effectiveness in restoring vital parameters to baseline.
Conclusion: The findings suggest that IIEP is an effective therapeutic approach for improving changes in Heart rate variability, and physical fitness level of young adults.
Keywords: Obesity, Integrated Intensive Exercise Protocol, BMI, Heart Rate Variability (HRV), Physical Fitness.
How to cite this article: Sachdeva S, Rishi P, Sonia, Kumar S, Exercise Induced Modulation of cardiac Autonomic control in Obese Adults-An Experimental Study through Heart Rate Variability: An Experimental Study. Int J Drug Deliv Technol. 2026;16(3s): 632-640; DOI: 10.25258/ijddt.16.3s.80