1 Department Of Biosciences And Biotechnology, Krishna University, Machilipatnam-521004, Andhra Pradesh, India.
Corresponding Author: Suseela Lanka, Email: susheelalankaku@gmail.com
Silver nanoparticles (agnps) have recently gained significant attention in the medical field due to their diverse biological properties. The present study aimed to green-synthesise and characterize agnps using the aqueous leaf extract of bruguiera gymnorhiza. In addition, the in vitro antibacterial, antioxidant, and antidiabetic activities of both the plant extract and its synthesized agnps were evaluated. The powdered leaves were extracted to obtain an aqueous extract, which served as a reducing and stabilizing agent for the synthesis of agnps using silver nitrate.
The synthesized nanoparticles were characterized using uv–visible spectroscopy, fourier-transform infrared spectroscopy (ftir), scanning electron microscopy with energy-dispersive x-ray analysis (sem–edx), transmission electron microscopy (tem), and x-ray diffraction (xrd). All experiments were conducted in triplicate (n = 3), and results are expressed as mean ± standard deviation. The uv–visible spectrum exhibited a surface plasmon resonance (spr) peak at 424 nm, confirming agnp formation. Ftir analysis indicated the involvement of functional groups such as c=o, c–h, and o–h in the reduction and capping processes. Sem and tem analyses revealed predominantly spherical nanoparticles, with sizes ranging from 10 to 50 nm and an average size of 17 nm. Edx analysis showed a characteristic silver peak at 3 kev, while xrd confirmed the crystalline nature of the nanoparticles.
Biological activity assays demonstrated that the synthesized agnps exhibited significantly enhanced antibacterial, antioxidant, and antidiabetic activities compared to the crude plant extract. Overall, the findings suggest that b. Gymnorhiza-mediated agnps possess promising therapeutic potential. Further studies are warranted to elucidate their underlying mechanisms and validate their efficacy through in vivo models.
Keywords: Bruguiera Gymnorhiza, Aqueous Leaf Extract, Green Synthesis, Silver Nanoparticles, Characterization, Antibacterial Activity, Antioxidant Activity, Antidiabetic Activity.
How To Cite This Article: Katta A, Lanka S. Biogenic Silver Nanoparticles From Bruguiera Gymnorhiza: Synthesis, Characterization, And Evaluation Of Antibacterial, Antioxidant, And Antidiabetic Activities. Int J Drug Deliv Technol. 2026;16(4):388. Doi: 10.25258/ijddt.16.4.39