1 Additional Professor, Dept Of Conservative Dentistry And Endodontics, Yenepoya Dental College, Yenepoya (Deemed To Be University). Email: bhatsreegowri@gmail.com
2 Senior Lecturer, Dept Of Conservative Dentistry And Endodontics, Yenepoya Dental College, Yenepoya (Deemed To Be University). Email: ranjanpadau@gmail.com
Background: The success of endodontic surgery largely depends on achieving an effective apical seal to prevent microleakage and reinfection. Mineral trioxide aggregate (mta) is widely regarded as the gold standard for root-end filling; however, newer bioactive materials such as activa™ bioactive restorative have been introduced with claims of improved handling and bioactivity.
Aim: To compare the sealing ability of activa bioactive restorative and mta angelus when used as root-end filling materials using confocal laser scanning microscopy (clsm).
Materials and Methods: Fifty-four extracted human single-rooted teeth were selected and randomly divided into two groups: activa bioactive restorative (n=27) and mta angelus (n=27). Following standardized root canal preparation, obturation, apical resection, and root-end cavity preparation, the respective materials were placed. Specimens were coated with nail varnish (except apical region) and immersed in 1% rhodamine b dye for one week. Teeth were then sectioned and evaluated under clsm to assess dye penetration. Statistical analysis was performed using student's t-test with significance set at p<0.05.
Results: A total of 43 samples were analyzed. The activa group demonstrated significantly higher mean dye penetration (28,215 ± 1,547 µm²) compared to the mta group (22,710 ± 1,314 µm²). The difference was statistically significant (t=12.4, p<0.001).
Conclusion: Within the limitations of this in vitro study, mta angelus exhibited superior sealing ability compared to activa bioactive restorative. Mta remains a reliable root-end filling material, especially in surgical environments where moisture control is challenging. Further clinical studies are required to validate the performance of activa bioactive restorative.
Keywords: Mta Angelus, Activa Bioactive Restorative, Root-End Filling, Sealing Ability, Microleakage, Confocal Laser Scanning Microscopy (Clsm), Dye Penetration, Endodontic Surgery, Bioactive Materials.
Source of support: None.
Conflict of interest: None.
How To Cite This Article: Sreegowri, Shyam Ranjan Sharma. In Vitro Comparison Of Sealing Ability Of Mta And Activa Bioactive Restorative As Root End Filling Materials: A Confocal Laser Scanning Microscopy (Clsm) Study. Int J Drug Deliv Technol. 2026;16(4):433-437. Doi: 10.25258/ijddt.16.4.42