1 Department Of Pharmaceutical Quality Assurance, Alard University School Of Pharmacy, Marunji, Tal. Mulshi, Pune (411057), Maharashtra, India.
2 Department Of Pharmaceutical Chemistry, Rjspm'S College Of Pharmacy, Dudulgaon, Pune (412105), Maharashtra, India.
3 Department Of Pharmaceutical Chemistry, Alard University School Of Pharmacy, Marunji, Tal. Mulshi, Pune (411057), Maharashtra, India.
4 Department Of Pharmaceutical Chemistry, School Of Pharmacy, Vishwakarma University Vu Pune (411048), Maharashtra, India.
5 Department Of Pharmacognosy, Rjspm'S College Of Pharmacy, Dudulgaon, Pune (412105), Maharashtra, India.
6 Department Of Pharmaceutical Chemistry, Dr. D. Y. Patil College Of Pharmacy Akurdi Pune (411035), Maharashtra, India.
Corresponding Author: Dr. Madhuri U. Shelar, Department Of Pharmaceutical Quality Assurance, Alard University School Of Pharmacy, Marunji, Tal. Mulshi, Pune (411057), Maharashtra, India. Email: madhurishelar70@yahoo.com
The burgeoning interest in nanotechnology has catalyzed extensive investigations into the fabrication and multifunctional applications of nanomaterials, particularly silver nanoparticles (agnps), owing to their distinctive physicochemical properties and broad-spectrum bioactivity. This study delineates the extraction, phytochemical standardization, and green synthesis of agnps employing the root extract of nardostachys jatamansi, a medicinal herb renowned for its diverse secondary metabolites. Initially, the root extract was meticulously prepared and standardized to ensure batch-to-batch consistency in the concentration of the bioactive constituents. The biosynthesis of agnps was facilitated via a sustainable, phytochemical-mediated reduction process in which the extract functioned as both a reducing and capping agent. The physicochemical attributes of the synthesized nanoparticles were comprehensively characterized using ultraviolet-visible (uv-vis) spectroscopy, x-ray diffraction (xrd), and transmission electron microscopy (tem) to elucidate their optical properties, crystalline nature, morphology, and particle size distribution. Furthermore, the antifungal potential of the synthesized agnps was evaluated against candida albicans to assess their therapeutic efficacy in vitro. These findings underscore a facile and eco-compatible approach for agnp synthesis, with promising implications for biomedical applications, environmental remediation, and catalytic systems.
Keywords: Silver Nanoparticles, Nardostachys Jatamansi, Green Synthesis, Antifungal Activity, Characterization.
How To Cite This Article: Bhagwat A, Shelar Mu, Kadam Jn, Nagare S, Gondhale-Karpe P, Dhumal Js, Jadhav Ny, Warude Bj. Extraction, Standardization And Synthesis Of Silver Nanoparticles From Root Extract Of Nardostachys Jatamansi. Int J Drug Deliv Technol. 2026;16(4):438-445. Doi: 10.25258/ijddt.16.4.43