A Clinical Study Of Cutaneous Manifestations In Chronic Renal Failure

Dr. Arishta Bala1, Dr. Roshini Rajendran2, Dr. Saranya M3*, Dr. Irene Nirmala Thomas4, Dr. Jenson Joseph J5, Dr. Nithya Priyadharshini6

1MD Dermatology Venereology Leprosy, Assistant Professor, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Sri Balaji Vidyapeeth deemed to be University, Puducherry, India
Email: arishtabala12@gmail.com
ORCID ID: 0009-0009-0769-2461
2MD Dermatology Venereology Leprosy, DNB(DVL), Senior Resident, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Sri Balaji Vidyapeeth deemed to be University, Puducherry, India
Email: roshrajkmc@gmail.com
ORCID ID: 0009-0007-6648-0309
3*MD Dermatology Venereology Leprosy, Associate Professor, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Sri Balaji Vidyapeeth deemed to be University, Puducherry, India (Corresponding Author)
Email: sharonpaul10@yahoo.co.in
ORCID ID: 0000-0002-8396-9356
Mobile: 9500713222
4MD Dermatology Venereology Leprosy, Associate Professor, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Sri Balaji Vidyapeeth deemed to be University, Puducherry, India
Email: irenenirmala26@yahoo.co.in
ORCID ID: 0000-0002-3508-3251
5MD Dermatology Venereology Leprosy, Associate Professor, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Sri Balaji Vidyapeeth deemed to be University, Puducherry, India
Email: jjjenson1389@gmail.com
ORCID ID: 0000-0002-1109-6445
6MD Dermatology Venereology Leprosy, Professor, Department of Dermatology, Shri Sathya Sai Medical College & Research Institute, Chengelpet, Tamilnadu, India 603108
Email: nithi12dr@gmail.com
ORCID ID: 0000-0002-0565-8931

Received: ; Revised: ; Accepted: ; Available Online:

ABSTRACT

BACKGROUND: Skin -mirror of internal disease and diagnosing the systemic disease by cutaneous manifestations has always fascinated clinicians. Chronic renal failure is a common medical problem due to its increased incidence.

AIMS AND OBJECTIVES: To study the cutaneous manifestations and their incidence in patients with chronic renal failure.

MATERIALS AND METHODS: Seventy five patients with CRF who attended the Department of Dermatology and Nephrology of our Institute were enrolled.

RESULTS: Among 75 patients, 69% were males and 31% were females with M:F ratio of 2.2:1. The common symptom was pruritus (82%), common cutaneous finding was pigmentary change (53%) and xerosis (44%). Acquired perforating dermatosis specific to chronic renal failure was seen in 9.3%. Significant number (20%) had gynecomastia. Hair changes, nail changes and oral mucosal changes were seen in 21.3%, 30.6%, 28% respectively. Brown arc was the most common nail change followed by half and half nails. Oral mucosal lesions was present in 28% with stomatitis. Fungal infection (20%) with tinea versicolor was the commonest presentation followed by viral infections (12%) and bacterial infection (5.3%).

CONCLUSION: Recognition and management of the dermatological manifestations vastly reduces the morbidity and also improve the cutaneous outcome in these patients.

Keywords: pruritis, xerosis, gynecomastia

How to cite this article: Bala A, Rajendran R, Saranya M, Thomas IN, Jenson JJ, Priyadharshini N, A Clinical Study Of Cutaneous Manifestations In Chronic Renal Failure. Int J Drug Deliv Technol. 2026;16(4s): 328-334; DOI: 10.25258/ijddt.16.4s.43