Effect of Nursing Educational Intervention on Knowledge and Preventive Behaviors Regarding Human Papillomavirus and Cervical Cancer Among Premenopausal Women

Randa Mohamed Abobaker1*, Nabila Salem Mohamed2, Naeima Mohammed Ahmed3, Aida Ahmed Mohamed4, Bataa Mahmoud Mohamed5, Fares Hameed D Alshammari6, Azza Mohamed El-Sayed Atwa7

1*College of Nursing, Department of Maternal and Child Health Nursing Department, University of Hafr Al-Batin, Kingdom of Saudi Arabia.
Email: randaabobakre@gmail.com
ORCID: https://orcid.org/0000-0003-2569-8196
(Corresponding Author)
2Professor of Obstetrics and Gynecological Nursing, Faculty of Nursing, Zagazig University, Egypt.
Associate Professor of Maternity Nursing, Nursing department, North Private College of Nursing, Arar city, Northern Province, Kingdom of Saudi Arabia.
Email: nabilahussien1012@gmail.com
ORCID: https://orcid.org/0009-0004-6814-7225
3Professor of Obstetrics and Gynecological Nursing, Faculty of Nursing, Zagazig University, Egypt.
Associate Professor of Maternity Nursing, Nursing department, North Private College of Nursing, Arar city, Northern Province, Kingdom of Saudi Arabia.
Email: naimamohammed@nec.edu.sa
ORCID: https://orcid.org/0009-0006-6582-6905
4Assistant professor of Medical and Surgical Nursing, Faculty of Nursing, Zagazig University, Egypt.
Associate Professor of Medical and Surgical Nursing, Nursing department, North Private College of Nursing, Arar city, Northern Province, Kingdom of Saudi Arabia. PhD, RN.
Email: aidaahmed@nec.edu.sa
ORCID: https://orcid.org/0009-0008-4691-8139
5Assistant professor of pediatrics Nursing, Faculty of Nursing, Zagazig University, Egypt.
Associate Professor of Pediatrics Nursing, Nursing department, North Private College of Nursing, Arar city, Northern Province, Kingdom of Saudi Arabia.
Email: bataamahmoud@nec.edu.sa
ORCID: https://orcid.org/0009-0006-3267-9398
6College of Nursing, Department of Medical, Surgical, and Critical Care Nursing, University of Hafr Al-Batin, Kingdom of Saudi Arabia.
Email: fhalshammari@uhb.edu.sa
ORCID: https://orcid.org/0000-0002-1223-1426
7Assistant professor of Obstetrics and Gynecology Nursing, Faculty of Nursing, Sohag University, Egypt
Email: Drazzaatwa@gmail.com

Received: ; Revised: ; Accepted: ; Available Online:

ABSTRACT

Background: Cervical cancer remains a significant global health challenge, particularly in low- and middle-income countries. Human papillomavirus (HPV) infection is the primary cause of cervical cancer, which is largely preventable through vaccination and screening. However, knowledge gaps and inadequate preventive behaviors persist among women in many regions.

Purpose: This study aimed to evaluate the effect of a nursing educational intervention on knowledge and preventive behaviors regarding HPV and cervical cancer among premenopausal women.

Methods: A quasi-experimental design with pre- and post-tests was employed. A convenience sample of 120 premenopausal women aged 40-50 years was recruited from the Gynecological Outpatient Clinic at a university hospital in Egypt. Data were collected using, firstly, structured questionnaires that included demographic characteristics. Secondly, assessing knowledge about HPV, cervical cancer, and thirdly, preventive health behaviors. The educational intervention was delivered through small-group sessions using lectures, discussions, and educational materials.

Results: The proportion of participants demonstrating satisfactory knowledge increased significantly from 38.3% pre-intervention to 71.7% post-intervention (p < 0.001). Statistically significant improvements were observed in knowledge about HPV immunization, cervical cancer definition, risk factors, diagnosis, treatment methods, and preventive health behaviors. Positive correlations were found between educational level and knowledge scores.

Conclusion: The nursing educational intervention effectively enhanced knowledge and preventive behaviors regarding HPV and cervical cancer among premenopausal women. These findings support the implementation of structured educational programs to improve cervical cancer prevention.

Implications for Nursing Practice: These findings highlight the critical role of maternity nurses in cervical cancer early detection and prevention through health education. Also, inform women about risks, signs, and encourage screening.

Keywords: Cervical cancer; educational intervention; human papillomavirus; knowledge; nursing education; preventive behaviors

How to cite this article: Abobaker RM, Mohamed NS, Ahmed NM, Mohamed AA, Mohamed BM, Alshammari FHD, Atwa AME, Effect of Nursing Educational Intervention on Knowledge and Preventive Behaviors Regarding Human Papillomavirus and Cervical Cancer Among Premenopausal Women. Int J Drug Deliv Technol. 2026;16(4s): 426-436; DOI: 10.25258/ijddt.16.4s.52