International Journal of Drug Delivery Technology
Volume 16, Issue 5, 2026

Pregnancy in Women with End-Stage Kidney Disease Receiving Maintenance Hemodialysis: A Five-Year Experience from a Tertiary Academic Hospital

Adinda Rahadina1, Agus Sulistyono2, Manggala Pasca Wardhana2, Widodo3, Adinda Rahadini3

1 Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia

2 Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia

3 Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, 60115, Indonesia

Received: 28th Feb, 2026; Revised: 6th March 2026; Accepted: 7th April, 2026; Available Online: 20th April, 2026

ABSTRACT

Objective:

To describe maternal characteristics, management, and perinatal outcomes of pregnancies complicated by stage V chronic kidney disease (CKD) receiving regular hemodialysis at a tertiary referral center.

Case:

This case series included 10 pregnancies (mean age 32 years; 90% multigravida). Chronic hypertension and prior preeclampsia were common backgrounds. All pregnancies ended before 37 weeks; half reached the third trimester. Preeclampsia occurred in 50% and anemia in all cases (mean pre-delivery Hb 7.64 g/dL; 20% severe). Among 8 live births, 77.5% had low birth weight; Apgar <7 occurred in 75% at 1 minute and 37.5% at 5 minutes. Dialysis frequency was 2–3 sessions/week.

Conclusion:

Pregnancy on dialysis remains high risk with frequent preterm birth and neonatal morbidity, requiring early referral and multidisciplinary care with optimized dialysis and maternal stabilization.

Keywords: chronic kidney disease, hemodialysis, pregnancy

How to cite this article: Rahadina A, Sulistyono A, Wardhana MP, Widodo W, Rahadini A. Pregnancy in Women with End-Stage Kidney Disease Receiving Maintenance Hemodialysis: A Five-Year Experience from a Tertiary Academic Hospital. Int J Drug Deliv Technol. 2026;16(5): 131-135. DOI: 10.25258/ijddt.16.5.14

Source of support: Nil.

Conflict of interest: None