1* Department of Food Technology, Rajalakshmi Engineering College, Thandalam, Chennai, Tamil Nadu, India. Email: bharathi.p@rajalakshmi.edu.in (Corresponding Author)
2 Department of Biotechnology, Karpaga Vinayaga College of Engineering and Technology, Chinna Kolambakkam, Padalam, Chengalpattu - 603308, Tamil Nadu, India. Email: senthilenvtce@gmail.com (Corresponding Author)
3 Department of Electronics and Communication Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Kancheepuram, Chennai – 602105, Tamil Nadu, India
4 Department of Electrical and Electronics Engineering, Solamalai College of Engineering, Madurai – 625020, Tamil Nadu, India
5 Department of Electronics and Communication Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Kancheepuram, Chennai – 602105, Tamil Nadu, India
The aim of present research is to study, compares and examines the antidiabetic properties of aqueous extracts from Syzygium cumini, Luffa acutangula, and Coccinia grandis, as well as their mechanisms of action. The conventional procedures for phytochemical screening, which include alkaloids, phenols, carbohydrates, flavanoids, saponins, amino acids, and steroids, were applied to the three plant samples. Syzygium cumini exhibited the highest concentration of quantitative test results. Aqueous extract sample's antioxidant activity was measured utilizing the DPPH and Phosphomolybdenum Reduction Assay methods. Based on the comparison of the antioxidant results of DPPH and Phosphomolbdenum, Coccinia grandis and Syzygium cumini were mixed and an antidiabetic assay was conducted. Using the glucose uptake assay, antidiabetic studies on cell lines have demonstrated a higher percentage of insulin absence.
Keywords: Diabetics, phytochemical analysis, antioxidant activity, antidiabetic assay, Good Health and Well-Being
How to cite this article: Bharathi P, Muniasamy SK, Naveen G, Ezhilmathi N, Maharajan PM. Evaluation of the phytochemical and antidiabetic properties of nano-based materials derived from Coccinia grandis, Luffa acutangula, and Syzygium cumini. Int J Drug Deliv Technol. 2026;16(5): 333-340. DOI: 10.25258/ijddt.16.5.35
Source of support: Nil.
Conflict of interest: None