1Research Scholar, Department of Pharmacy, Madhav University, Pindwara, Sirohi, Rajasthan.
2Professor and Principal, Institute of Pharmacy, Madhav University, Pindwara, Sirohi, Rajasthan.
The present study aimed to evaluate the phytochemical constituents and antioxidant potential of different solvent extracts of Parmotrema perlatum. The powdered lichen material was successively extracted using hexane, chloroform, ethyl acetate, ethanol, and water, and the percentage yield was determined. Preliminary phytochemical screening revealed the presence of flavonoids in all extracts, while phenolic compounds were predominantly detected in ethanolic and aqueous extracts. Thin Layer Chromatography (TLC) analysis confirmed the presence of flavonoids and phenolic constituents by comparing Rf values with standard quercetin and gallic acid. Quantitative estimation demonstrated that the ethanolic extract possessed the highest total phenolic and flavonoid content. The antioxidant activity was evaluated using DPPH, nitric oxide, and hydrogen peroxide scavenging assays, with ascorbic acid used as the standard. The ethanolic extract exhibited concentration-dependent radical scavenging activity in all assays. Although its DPPH and nitric oxide scavenging activities were moderate compared to ascorbic acid, it showed comparatively strong hydrogen peroxide scavenging activity. The findings suggest that the antioxidant potential of Parmotrema perlatum is attributed to its rich phenolic and flavonoid content, highlighting its potential as a natural source of antioxidant compounds for pharmaceutical applications.
Keywords: Parmotrema perlatum, Phytochemical screening, Thin Layer Chromatography (TLC), Total phenolic content, Total flavonoid content, DPPH assay, Nitric oxide scavenging, Hydrogen peroxide scavenging, Antioxidant activity
How to cite this article: Ghate AC, Dwivedi AK. Phytochemical Screening And Evaluation Of Antioxidant Activity Of Different Solvent Extracts Of Parmotrema Perlatum. Int J Drug Deliv Technol. 2026; 16(5s): 898-905; DOI: 10.25258/ijddt.16.5s.109
Source of support: Nil.
Conflict of interest: None