1Research scholar, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, India
2*Professor, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, India
Hyperlipidemia is a growing health challenge in the world especially in developing nations such as India. This paper is to highlight the research work towards antihyperlipidemic properties of hexane and ethanol floral extracts of Capparis decidua on high-fat diet-induced hyperlipidemic Wistar albino rats. The preliminary qualitative phytochemical analysis revealed that the ethanolic extract contains high levels of flavonoids and phenolic compounds, whereas the hexane extract is composed primarily of oils and steroids. As per the experimental work after 21 days of the drug treatment and mean body weight was measured at every 5 days of drugs treatment based on the results of blood testing the ethanolic floral extract of Capparis decidua, particularly at high dose, significantly improved lipid profiles by reducing total cholesterol, triglycerides, LDL, and VLDL, and by increasing HDL levels, similar to Atorvastatin which is considered to be standard drug. Conversely, the hexane extract has not shown significant effects like the ethanolic extract. These findings suggest the potential use of Capparis decidua flowers in the natural management of hyperlipidemia.
Keywords: Antihyperlipidemia, Total cholesterol, Low density lipoproteins, High density lipoproteins.
How to cite this article: Gupta S, Surendra G, Assessment of Anti-hyperlipidemic property from the flower extracts of Capparis decidua in Experimental animals using Diet induce hyperlipidemic model. Int J Drug Deliv Technol. 2026; 16(5s): 919-924; DOI: 10.25258/ijddt.16.5s.112
Source of support: Nil.
Conflict of interest: None