1Assistant Professor, RIMS Ranchi
2Junior Resident, CCL Gandhi Nagar
3*Assistant Professor, Medicine, NSMCH, Jamshedpur. Email: sandephoro29@gmail.com
4Consultant, CCL Gandhi Nagar
Introduction: Hypertension is a major global health concern linked to cardiovascular and renal morbidity. Serum uric acid has been implicated in its pathogenesis through endothelial dysfunction and metabolic mechanisms. Body mass index and age may modify this relationship. This study evaluates serum uric acid levels in essential hypertension with reference to age and body mass index (BMI).
Material and Method: This hospital-based cross-sectional study included 100 participants (50 hypertensive, 50 controls). Blood pressure (BP) and BMI were recorded, and fasting serum uric acid was measured using an automated analyzer. Hyperuricemia was defined as >6.5 mg/dL. Data were analyzed using appropriate statistical tests, with p < 0.05 considered significant.
Result: Among 100 participants (50 hypertensive, 50 controls), hypertensive subjects had significantly higher serum uric acid (6.88±1.63 vs 5.35±1.83 mg/dl; p=0.0001). Hyperuricemia was more prevalent in cases (62% vs 26%; p=0.0002). Serum uric acid (SUA) showed positive correlation with systolic BP (r=0.45) and diastolic BP (r=0.44). Hypertension (OR 4.07) and obesity (OR 7.00) independently predicted hyperuricemia, while age and gender were not significant predictors.
Conclusion: Elevated serum uric acid levels were significantly associated with essential hypertension, particularly among obese individuals. Hypertension and increased BMI independently predicted hyperuricemia, while age showed no independent association. Routine uric acid assessment may enhance cardiovascular risk stratification and guide early preventive interventions.
Keywords: Hypertension, blood pressure, uric acid, age, BMI, obesity
How to cite this article: Prasad R, Satish RK, Horo SM, Singh S. Serum Uric Acid and Its Association with Age and Body Mass Index in Essential Hypertension. Int J Drug Deliv Technol. 2026; 16(5s): 998-1005; DOI: 10.25258/ijddt.16.5s.122
Source of support: Nil.
Conflict of interest: None