This study explores the correlation between hopelessness, depression, and obsessive-compulsive disorder (OCD) in patients who also suffer from eczematous lesions, specifically hand eczema (HE). OCD is a chronic mental health condition marked by intrusive thoughts and compulsive behaviors, which can significantly impair daily functioning. Eczematous lesions, particularly hand eczema, exacerbate this impact by influencing patients' psychological well-being, leading to distressing symptoms such as itching, pain, and a decrease in quality of life (QoL). The aim of this research was to investigate the psychological burden of OCD in patients with eczematous lesions, focusing on how hopelessness and depression affect both the severity of the skin condition and the overall quality of life. Through a cross-sectional study design, 100 adult participants were assessed for depression and hopelessness using standardized questionnaires such as PHQ-9, GAD-7, and HADS-M. The study revealed a significant positive correlation between depression, hopelessness, and the severity of OCD symptoms. Additionally, the presence of eczematous lesions exacerbated the psychological distress experienced by these patients. This paper highlights the importance of recognizing and addressing the psychological components in the management of OCD patients with skin disorders, emphasizing a multidisciplinary approach for effective treatment and support.
Keywords: Obsessive-Compulsive Disorder (OCD), Depression, Hopelessness, Eczematous Lesions, Hand Eczema, Psychological Burden, Quality of Life (QoL), Comorbidity, Psychodermatology and Mental Health.
How to cite this article: Aijaz S, Alhudhayyiri ZMB, Alenezi AMM, Alanazi AKM, Alanazi RAQ, Alanazi WGA, Alenezi DFK, Alenezi AAA, Alanazi ZM, Aldhabyan FNB, Correlation of Hopelessness and Depression in Patients of Ocd Having Eczematous Lesion. Int J Drug Deliv Technol. 2026;16(5s): 149-160. DOI: 10.25258/ijddt.16.5s.18