Correlation between Motor Evoked Potentials and Upper Extremity Functional Outcome Measures in Chronic Stroke: A Cross Sectional Study

Rania Mamdouh ^1,2, Hoda M. Zakaria ², Ebtesam M. Fahmy ³, Mostafa M. ElKholy ⁴, Sahar Mohamed Adel Elhakk ^5,6, Marwa Mostafa ², Shreen Ibrahim Taha ^1,7

¹Department of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Beni Suef University, Egypt.
²Department of Physical Therapy for Neurology, College of Physical Therapy, Cairo University, Egypt.
³Department of Neurology, Faculty of Medicine, Cairo University, Egypt.
⁴Department of Neurophysiology, Faculty of Medicine, Beni Suef University, Egypt.
⁵Department of Basic Science, Faculty of Physical Therapy, Galala University, Suez, Egypt.
⁶Department of Basic Science, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
⁷Department of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Badr University, Egypt.

Received: 18th Dec, 2025; Revised: 7th Feb 2026; Accepted: 12th Feb, 2026; Available Online: 28th Feb, 2026

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ABSTRACT

Objectives: Stroke is one of the most neurological diseases that causes upper extremity impairment. In order to set an individualized treatment program for these impairments, it may be crucial to use and determine the association between the different assessment tools of upper extremity function. The aim of our study was to evaluate any correlation of Motor evoked potentials with the Fugl-Meyer Assessment of the Upper Extremity (FMA-UE) and the Wolf Motor Function Test (WMFT) in patients with chronic stroke.

Methods: Forty chronic ischemic stroke patients, aged 45 to 60 were included. Wolf Motor Function Test and Fugl-Meyer Assessment of the Upper Extremity and Suprathreshold Motor Evoked Potentials (sMEPs) were measured for all patients.

Results: A significant positive correlation among FMA-UE and sMEPs (r = 0.346, p = 0.028) was found. There was no significant relation between WMFT and sMEPs (r = 0.034, p = 0.834).

Conclusion: sMEPs was found to be related with FMA-UE scale and can be a good indicator for functional impairment level in chronic stroke patients.

Keywords: Stroke, Motor Evoked potentials, Wolf Motor Functional Test, Fugl-Meyer Assessment of the Upper Extremity.

How to cite this article: Mamdouh R, Zakaria HM, Fahmy EM, ElKholy MM, Elhakk SMA, Mostafa M, Taha SI. Correlation between motor evoked potentials and upper extremity functional outcome measures in chronic stroke: a cross sectional study. Int J Drug Deliv Technol. 2026;16(5s): 344-347; DOI: 10.25258/ijddt.16.5s.45

Source of support: None.

Conflict of interest: None