*Corresponding Author: Vidya Umesh Patil, Department of Pharmacognosy, Ashokrao Mane College of Pharmacy, Peth Vadgaon, Kolhapur, India.
The growing prevalence of metabolic syndrome and oxidative stress–associated disorders has increased interest in evidence-based polyherbal formulations. Moringa oleifera and Murraya koenigii are nutritionally rich medicinal plants with complementary phytochemical profiles that justify their combined use in a standardized tablet formulation. M. oleifera is abundant in flavonoids, glucosinolates, vitamins, and essential minerals that exhibit antioxidant, anti-inflammatory, hepatoprotective, and glycaemic regulatory activities, whereas M. koenigii contains carbazole alkaloids and phenolic compounds associated with antidiabetic, lipid-lowering, antimicrobial, and cytoprotective effects. Comparative experimental evidence suggests that their combination enhances antioxidant defense, improves insulin sensitivity, modulates glucose metabolism, and supports lipid regulation more effectively than single extracts. Dry leaf powders offer higher nutrient density and improved stability for pharmaceutical development compared with fresh leaves. Advances in phytochemical standardization and analytical fingerprinting, along with optimized tablet systems and emerging nano-based delivery approaches, further enhance bioavailability and therapeutic consistency. Although preclinical findings strongly support synergistic benefits, large-scale randomized clinical trials remain limited. Overall, the Moringa–Curry leaf polyherbal tablet represents a scientifically rational nutraceutical strategy for metabolic and oxidative stress management, warranting further dose optimization, pharmacokinetic evaluation, and clinical validation to establish its evidence-based therapeutic potential.
Keywords: Moringa oleifera, Murraya koenigii, polyherbal tablet, phytochemicals, antioxidant, metabolic health, nutraceutical formulation, functional foods.
How to cite this article: Patil VU. Therapeutic potential of Moringa oleifera and Murraya koenigii: a comprehensive review of phytochemistry, pharmacology and formulation strategies. Int J Drug Deliv Technol. 2026;16(6s): 106-116; DOI: 10.25258/ijddt.16.6s.13
Source of support: None.
Conflict of interest: None