1Assistant Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P. India.
2Assistant Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P. India.
3Assistant Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P., India.
4Assistant Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P., India.
5Research Scholar, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P., India.
6Research Scholar, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P., India.
7Research Scholar, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences &Technology, Baddi Makhnumajra- 173205, H.P., India.
8Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences &Technology, Baddi Makhnumajra- 173205, H.P., India.
9Associate Professor, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi Makhnumajra- 173205, H.P., India.
Alopecia, or hair loss, is a common medical condition that can affect anyone, regardless of age and sex. Although it is not a life-threateningcondition, it can strongly affect a person’s confidence, self-image and well-being. Hair loss can occur due to interruption of the natural hair growth cycle due to several factors such as genetics, hormonal changes, autoimmune responses, stress, nutritional deficiencies, medications, infections, or long-term hairstyling practices. Alopecia may be temporary or permanent based on the cause.
They can be classified into non-scarring alopecia and scarring alopecia. With proper management, non-scarring alopecia, which includes androgenetic alopecia, alopecia areata, telogen effluvium, traction alopecia, anagen effluvium, and trichotillomania, has a good chance in terms of regrowth of hair follicles. Early diagnosis of scarring alopecia, such as lichen planopilaris and frontal fibrosing alopecia is important since it involves an inflammatory stage with permanent destruction of the hair follicles. Inflammation leads to an imbalance in hair production. Diagnosis can be conducted via laboratory testing, trichoscopy, clinical examination, and sometime a scalp biopsy. The treatment methods have increased consequently over the years. The conventional treatment methods such as minoxidil and finasteride are in common usage, but other developments such as JAK inhibitors, PRP therapy, stem cell therapy, low-level laser therapy, and topical/systemic immunotherapy can provide better results. Hair transplants are considered an efficient treatment for chronic hair loss in cases of androgenetic alopecia. Apart from conventional therapies, aloe vera, amla, bhringaraj, fenugreek, onion juice, garlic, and coconut oil are used in combination for their nutrient-rich properties for hair and improving qualities of hair.
Keywords: Alopecia, hair loss, androgenetic alopecia, alopecia areata, telogen effluvium, hair growth cycle, hormonal imbalance, DHT, JAK inhibitors, PRP therapy, stem cell therapy, immunotherapy, hair transplantation, scarring alopecia, non-scarring alopecia, herbal remedies.
How to cite this article: Sharma A, Sharma S, Sharma S, Kritika, Sharma A, Vandana, Ghanshyam, Mishra R, Sharma B, Clinical Perspectives on Alopecia: From Hair Follicle Biology to Advanced Therapies. Int J Drug Deliv Technol. 2026;16(6s): 247-265; DOI: 10.25258/ijddt.16.6s.31
Source of support: Nil
Conflict of interest: None