International Journal of Drug Delivery Technology
Volume 16, Issue 6s, 2026

To Evaluate the effect of Vilepi as an Ahara Dravya in the management of Karshyarog Non-Randomized Double-Arm Clinical Study

Dr Dharmendra Binjhwar1, Dr Sasmita Tripathy2, Dr Vibha Pali3, Dr Kush Kumar Sahu4, Dr Harish Sharan Sahu5

1PG Scholar, Department of Swasthavritta and Yoga, Shri NPA Government Ayurved College, Raipur, Chhattisgarh, India
dharmendrabinjhwar205@gmail.com

2Reader & HOD, Department of Swasthavritta and Yoga, Government Ayurved College, Bilaspur, Chhattisgarh, India
Sasmita1980@gmail.com

3Lecturer, Department of Swasthavritta and Yoga, Shri NPA Government Ayurved College, Raipur, Chhattisgarh, India
Vibhapali@gmail.com

4PG Scholar, Department of Swasthavritta and Yoga, Shri NPA Government Ayurved College, Raipur, Chhattisgarh, India

5PG Scholar, Department of Swasthavritta and Yoga, Shri NPA Government Ayurved College, Raipur, Chhattisgarh, India
hsharishsahu56@gmail.com


ABSTRACT

Background: Karshya Roga, a Vata-predominant condition described in Ayurveda, is clinically comparable to undernutrition and emaciation. Impaired digestion and nutrient assimilation result in reduced body mass and functional capacity, posing a significant health burden in developing countries.

Objective: To evaluate the efficacy of Vilepi as a nutritional intervention in patients with Karshya Roga compared to routine dietary management.

Methods: A non-randomized, open-label, double-arm interventional study was conducted on 40 patients. Group A (n=20) received routine dietary management, while Group B (n=20) received Vilepi for 60 days. Subjective parameters and objective anthropometric measurements (body weight, BMI, MUAC) were assessed. Bioanalytical investigations included hemoglobin percentage (Hb%), erythrocyte sedimentation rate (ESR), and random blood sugar (RBS). Intra-group statistical analysis was performed.

Results: Group B showed highly significant improvement in subjective parameters and anthropometric indices, with a marked reduction in ESR. Changes in Hb% and RBS were not significant.

Conclusion: Vilepi demonstrated superior nutritional and bioanalytical benefits, suggesting its potential role in managing undernutrition and Emaciation.

Keywords: Undernutrition, Emaciation, Vilepi, Dietary Intervention, BMI, Bioanalytical Parameters

How to cite this article: Binjhwar D, Tripathy S, Pali V, Sahu K K, Sahu H S, To Evaluate the effect of Vilepi as an Ahara Dravya in the management of Karshyarog Non-Randomized Double-Arm Clinical Study. Int J Drug Deliv Technol. 2026;16(6s): 384-387; DOI: 10.25258/ijddt.16.6s.40.

Source of support: Nil

Conflict of interest: None