International Journal of Drug Delivery Technology
Volume 16, Issue 6s, 2026

Understanding Hypothyroidism as a Manifestation of Mandagni: Evidence from a Case Study

Dr. Aanchal Gupta1, Dr. Sanjay Shukla2, Dr. Rupendra Chandrakar3, Dr. Rajesh Sao4

1Post-Graduate Scholar, Dept. of Roga Nidana Evam Vikriti Vigyana, Shri NPA Govt. Ayurved College, Raipur, Chhattisgarh, India

2Reader, Dept. of Roga Nidana Evam Vikriti Vigyana, Shri NPA Govt. Ayurved College, Raipur, Chhattisgarh, India

3Reader, Dept. of Samhita Siddhant, Shri NPA Govt. Ayurved College, Raipur, Chhattisgarh, India

4Post-Graduate Scholar, Dept. of Roga Nidana Evam Vikriti Vigyana, Shri NPA Govt. Ayurved College, Raipur, Chhattisgarh, India

ABSTRACT

A 31 years old patient, came with symptoms suggestive of hypothyroidism, including heaviness in abdomen and whole body, constant fatigue, constipation, and increasing body weight, was managed using a single Ayurvedic formulation containing Ashwagandha, Triphala, Shilajit, Guggul, and Kanchanar along with recommended Pathya-Apathya regimen as mentioned in Bhaishajya Ratnawali Agnimandhya Rogadhikara. The treatment plan was based on Agni Deepana, Ama Pachana, Kapha-Medohara, Rasayana, and Srotoshodhana (especially Rasavaha Strotas) principles. Clinical assessment and serum TSH levels were monitored over a period of two months. Following the treatment plan, shows symptomatic improvement, particularly in heaviness in abdomen, energy levels and digestive regularity. A noticeable reduction in serum TSH levels was noted, although values remained slightly high at the end of the observation period. No adverse effects were reported. The observed clinical and biochemical changes suggest a potentially supportive role of Ayurvedic intervention in managing conditions correlated with hypothyroidism. However, as this is a single case observation, larger controlled studies are required to prove these findings and evaluate repeatability.

Keywords: Hypothyroidism, Agnimandya, Kapha-Meda vriddhi, Ayurveda, TSH, Rasayana therapy.

How to cite this article: Gupta A, Shukla S, Chandrakar R, Sao R, Understanding Hypothyroidism as a Manifestation of Mandagni: Evidence from a Case Study. Int J Drug Deliv Technol. 2026;16(6s): 388-396; DOI: 10.25258/ijddt.16.6s.41

Source of support: Nil

Conflict of interest: None