International Journal of Drug Delivery Technology
Volume 16, Issue 6s, 2026

Assessing the Prevalence and Determinants of Depression and Anxiety Disorders among Adults in Urban India: A Mixed-Methods Study

Dillon Chikocho1, Ankush Barthwal2, Shivshankar Tiwari3, Saloni4, Zonunpari Ralte5, Neha6, Diksha Chetry7

1Student of Masters of Hospital Administration, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: dillonzivai@gmail.com
ORCID ID: 0009-0003-7419-7045

2Student of Masters of Public Health, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: ankushbarthwal8@gmail.com
ORCID ID: 0009-0003-5588-6646

3Assistant Professor, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, India
Email: shivshankartiwari@gmail.com
ORCID ID: 0009-0006-4248-3487

4Student of Masters of Public Health, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: Salonayyy2003@gmail.com
ORCID ID: 0009-0004-0267-5391

5Student of Masters of Hospital Administration, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: raltezonunpari1@gmail.com
ORCID ID: 0009-0009-3320-9699

6Student of Masters of Hospital Administration, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: vneha4762@gmail.com
ORCID ID: 0009-0005-4768-9065

7Student of Masters of Hospital Administration, Uttaranchal College of Health Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
Email: dikshachetry5@gmail.com
ORCID ID: 0009-0000-4822-4458


ABSTRACT

Background: Rapid urbanization in India has precipitated a transition in disease burden, with common mental disorders (CMDs) like depression and anxiety emerging as significant public health challenges. While quantitative studies have estimated prevalence, there is a paucity of mixed-methods research exploring the nuanced socio-cultural determinants of these disorders in the complex urban Indian context.

Methods: This study employed an Explanatory Sequential Mixed-Methods Design. Phase I involved a cross-sectional survey of 1,200 adults across three metropolitan cities (Mumbai, Delhi, Bangalore) using the PHQ-9 and GAD-7 instruments. Phase II involved 30 In-Depth Interviews (IDIs) and 5 Focus Group Discussions (FGDs) to explore the lived experiences and determinants of distress.

Results: The prevalence of depression and anxiety was found to be 15.2% and 12.8%, respectively, with comorbidity at 8.4%. Significant determinants included female gender (AOR: 1.8), financial instability (AOR: 2.1), and migration status (AOR: 1.6). Qualitative analysis revealed three core themes: "The Urban Paradox of Isolation," "Economic Precarity and Performance Pressure," and "Stigma as a Barrier to Care."

Conclusion: The high burden of CMDs in urban India is driven by a unique interplay of structural urban stressors and shifting social dynamics. Interventions must move beyond clinical treatment to address upstream urban determinants.

Keywords: Depression, Anxiety, Urban India, Mixed-Methods, Social Determinants, Public Health.

How to cite this article: Chikocho D, Barthwal A, Tiwari S, Saloni, Ralte Z, Neha, Chetry D, Assessing the Prevalence and Determinants of Depression and Anxiety Disorders among Adults in Urban India: A Mixed-Methods Study. Int J Drug Deliv Technol. 2026;16(6s): 442-446; DOI: 10.25258/ijddt.16.6s.45

Source of support: Nil

Conflict of interest: None