1Danish Azad, School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
Email: azad.danish@gmail.com
2Dr. Ritu M. Gilhotra, School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
Email: ritu.gilhotra@mygyanvihar.com
3Dr. Prashant Kumar Dhakad, School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.
Email: dhakadprashant654@gmail.com
Background: The adverse cardiovascular events are greatly enhanced by poor medication compliance among coronary artery disease (CAD) patients. Clinical pharmacists can play an vital role in enhancing adherence and buttressing the secondary prevention strategies through organized educational interventions. Objectives of the study was to evaluate the Patients with coronary artery disease who receiving conventional treatment in the SPEICAD and to assess how a structured educational intervention conducted by pharmacists affects medication adherence and clinical outcomes.
Methods: This prospective cross-sectionalstudy (SPEICAD) was done in a tertiary care hospital in Jaipur, India, and lasted 12 months. All CAD patients (n = 330) were randomized in equal proportion between two groups (Intervention: pharmacist-delivered education and follow-ups and Standard Care). The intervention was in the form of structured counseling, goal setting that was individualized, SMS reminders, clinical follows up that was done periodically. Primary outcomes measures were medication adherence and blood pressure control.
Results: After a 12 months follow-up period, the proportion of patients were 330 (165 per group), most were male (76.4%), aged between 50–70 years, and belonged to the upper-middle socioeconomic class. Eligible participants were adult inpatients with CAD discharged on cardioprotective drugs, while pregnant, lactating, and non-consenting patients were excluded. Medication adherence was consistently higher in the intervention group, with significant improvements in statin, beta-blocker, ACEI/ARB, and aspirin use, along with better blood pressure control compared to standard care. The levels of systolic and diastolic blood pressure were also controlled in the intervention arm better. There were no missing data and the analysis was made on the whole set of data.
Conclusion: Pharmacist-led educational interventions significantly improve adherence and clinical outcomes in CAD patients. Integrating such patient-centered strategies into routine care can enhance secondary prevention and long-term cardiovascular health.
Keywords: coronary artery disease, medication adherence, secondary prevention, SPEICAD
How to cite this article: Azad D, Gilhotra R M, Dhakad P K, Secondary Prevention Through Improving Adherence to Prescribed Cardio Protective Medication, Multifactorial or Polly-Interventions Following Percutaneous Coronary Intervention-Post PTCA At Discharge- A Single Centric Study. Int J Drug Deliv Technol. 2026;16(6s): 471-478; DOI: 10.25258/ijddt.16.6s.49.
Source of support: Nil
Conflict of interest: None