1*Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science and Technology and Advanced Studies, Pallavaram, Chennai, India
2,3,4,5IV Year B.Pharmacy, School of Pharmaceutical Sciences, Vels Institute of Science and Technology and Advanced Studies, Pallavaram, Chennai, India
This study shows novel herbal in-situ gel for the prevention and treatment of gastric ulcers is formulated and evaluated. The study concentrated on utilizing the well known anti-ulcer, anti-inflammatory, and anti-oxidant qualities of jamun fruit and pomegranate peel natural extracts by combining them in a gel matrix. Using in-situ gelation technology, the gel increases the bioavailability and effectiveness of the herbal compounds by allowing for targeted and sustained drug release in response to physiological stimuli like pH and temperature. Several natural polymers were used to optimize the formulation and both in-vitro and in-vivo techniques were used to evaluate its physical, chemical and biological characteristics. Because of its non toxic nature and ease of administration, the results demonstrated notable gastro protective, healing effects, improved anti-oxidant level and enhanced patient compliance.
KEYWORDS: Gastric Ulcers, Pomegranate Peel Extract, Herbal in-situ gel, Sustained Drug Release, Anti-Oxidant Properties.
How to cite this article: Monisha J, Keerthana J, Madhumitha V, Divya K, Dharmaraj K. Formulation and Evaluation of Herbal Insitu Gel with Gastro Protective Activity. Int J Drug Deliv Technol. 2026;16(7s): 964-968; DOI: 10.25258/ijddt.16.7s.103
Source of support: None
Conflict of interest: None