International Journal of Drug Delivery Technology
Volume 16, Issue 7s, 2026

Preparation and Standardization of the Dosage Form of a Liquid Extract from the Aboveground Part of Cultured Echinacea purpurea

Tadjiyeva Sevara 1, Sidametova Zaynab 1, Mirakilova Dilfuza 2, Rustamov Ibrokhim 1, Nurmatov Shovkat 1, Avazova Takhmina 3, Bafayev Jamshed 4

1Department of Pharmacognosy and Standardization of Drugs, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan.
Email: pharma.s.tadjiyeva@mail.ru; sidametovazaynab81@gmail.com; ibrokhim.rustamov.60@mail.ru; savkatzon89@gmail.com

2Laboratory of Drug Standardization and Quality Control, Institute of Chemical and Pharmaceutical Research, Tashkent, Uzbekistan.
Email: dilfuzamirakilova3005@gmail.com

3Department of Therapy, Cardiology and Functional Diagnostics with a Course in Cardiac Surgery of FPGE, PhD in Medical Sciences, Samarkand State Medical University, Samarkand, Uzbekistan.
Email: takhminochka80@gmail.com

4Department of Internal Medicine in Family Medicine, Bukhara State Medical Institute, Bukhara, Uzbekistan.
Email: jamshed_bafayev@bsmi.uz


ABSTRACT

Echinacea purpurea is a medicinal plant that has been widely used in traditional herbal practices due to its potential therapeutic properties. The plant is known to contain several biologically active compounds that may contribute to its reported health benefits, particularly in supporting immune function. Because the chemical composition of herbal materials can vary depending on processing and formulation methods, proper preparation and standardization of plant-based products are essential to ensure consistent quality and effectiveness.

The present study was undertaken to develop and standardize a liquid dosage formulation prepared from Echinacea purpurea. The work involved the extraction of plant constituents using an appropriate solvent system followed by the preparation of a stable liquid formulation suitable for oral administration. Various analytical procedures were applied to evaluate the quality of the extract and the finished product. These assessments included organoleptic examination, physicochemical evaluation, and preliminary phytochemical screening in order to identify the major classes of secondary metabolites present in the extract.

The results indicated that the prepared extract contained several important phytochemical groups such as phenolic compounds, flavonoids, polysaccharides, and other secondary metabolites commonly associated with medicinal activity. The formulated liquid dosage form demonstrated acceptable physical characteristics, including appropriate appearance, homogeneity, and stability under normal storage conditions. These findings suggest that the selected extraction and formulation procedures were suitable for producing a consistent herbal preparation.

Overall, the study provides a systematic approach for the preparation and analytical standardization of a liquid dosage form derived from Echinacea purpurea. The findings contribute to the development of reliable herbal formulations and highlight the importance of quality control in the production of plant-based medicinal products. Further research involving advanced analytical methods and biological evaluation may help to expand the understanding of the therapeutic potential of this medicinal plant.

Keywords: Echinacea purpurea, phytochemical standardization, hydro-ethanolic extraction, cichoric acid, alkamides, herbal liquid extract, HPLC analysis, medicinal plants.

How to cite this article: Sevara T, Zaynab S, Dilfuza M, Ibrokhim R, Shovkat N, Takhmina A, Jamshed B. Preparation and standardization of the dosage form of a liquid extract from the aboveground part of cultured Echinacea purpurea. Int J Drug Deliv Technol. 2026;16(7s): 295-302; DOI: 10.25258/ijddt.16.7s.33

Source of support: Nil.

Conflict of interest: None