International Journal of Drug Delivery Technology
Volume 16, Issue 8s, 2026

Prevalence of Avascular Necrosis of Femoral Head in Diabetic Patients Who Have Undergone Kidney Transplant

1 Shruti Sudhir Dubal, 2 Dr. Poonam Patil

1Final Year Student, Krishna College of Physiotherapy, KVV, 415539, Agashivnagar, Malkapur, Maharashtra, India. Email: @gmail.com

2Associated Professor, Department of Cardiopulmonary, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Karad (Corresponding Author). Email: @gmail.com


ABSTRACT

BACKGROUND: Avascular necrosis (AVN), or osteonecrosis, is the death of bone tissue due to reduced blood supply, commonly affecting the femoral head. It leads to bone collapse, joint dysfunction, and chronic pain. Kidney transplant patients, especially those with diabetes, are at increased risk due to prolonged use of corticosteroids and other immunosuppressive drugs. Additionally, vascular complications and metabolic imbalances in diabetic individuals may further contribute to AVN development. Despite its clinical importance, awareness of AVN in post-kidney transplant patients remains low. Early diagnosis is essential to prevent joint damage and disability. This study focuses on determining the prevalence of femoral head AVN in diabetic kidney transplant patients in Satara district, aiming to enhance awareness and guide early intervention.

OBJECTIVE:
1. To find out how prevalent is avascular necrosis of femoral head in diabetic patients among people undergone kidney transplant.
2. To calculate the prevalence of AVN in post-transplant patients.
3. To calculate the percentage of post kidney transplant patients who have developed AVN compared to overall population.

METHODOLOGY: A retrospective observational study was conducted in Satara using simple random sampling. A total of 49 diabetic post-kidney transplant patients aged 25–50 years were included. Exclusion criteria were metallic joint replacement, other bone diseases, and pre-transplant status. Data collection involved a validated online questionnaire, MRI reports, and consent forms. After obtaining ethical approval, eligible participants were informed, consented, and given the questionnaire. Responses were analysed statistically to assess the prevalence of femoral head avascular necrosis.

RESULT: The study included 49 participants with a mean age of 36.5 years and a standard deviation of 5.272. The p-value was found to be greater than 0.10, indicating no statistically significant difference. All 49 participants (100%) responded "Yes" to participating in the study. Regarding awareness and experience, 49% reported relevant symptoms or knowledge, while 0% reported none. In terms of transplant status, 100% of participants were post-transplant. Only 6.1% of participants reported having a history of fracture, joint pain, or complications such as AVN, while 93.9% did not. Notably, none of the participants had any metallic joint replacements. These findings suggest that while a significant portion of post-transplant diabetic patients reported relevant joint-related issues, the overall prevalence of complications such as AVN remains relatively low in this sample.

CONCLUSION: Study found hundred percentages of responses. A very few people having history of hip pain. Among 26.5% females and 73.5% males, 6.12% of patients suffering through post kidney transplant avascular necrosis.

KEYWORDS: Avascular Necrosis, Femoral Head, Kidney Transplantation, Diabetic Patients, Prevalence Study

How to cite this article: Dubal SS, Patil P. Prevalence of Avascular Necrosis of Femoral Head in Diabetic Patients Who Have Undergone Kidney Transplant. Int J Drug Deliv Technol. 2026;16(8s): 997-1000; DOI: 10.25258/ijddt.16.8s.112

Source of support: Nil.

Conflict of interest: None