1Department of Pedodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 160, Poonamallee High Road, Vellappanchavadi, Chennai 77. E-mail: 152001048.sdc@saveetha.com
2Associate Professor, Department of Pedodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 160, Poonamallee High Road, Vellappanchavadi, Chennai 77, Tamilnadu, India. E-mail: rameshr.sdc@saveetha.com
Background: Dental caries and endodontic infections caused by Streptococcus mutans and Enterococcus faecalis, respectively, remain a significant public health concern. Natural products, including plant extracts, have gained attention for their potential antimicrobial properties. Cassia auriculata, a medicinal plant rich in bioactive compounds, has been investigated for its antibacterial properties. This study aimed to compare the antimicrobial efficacy of aqueous and ethanolic extracts of Cassia auriculata against Streptococcus mutans and Enterococcus faecalis.
Aim: To evaluate aqueous and ethanolic extract of Cassia auriculata against Streptococcus mutans and Enterococcus faecalis.
Method: Aqueous and ethanolic extracts of Cassia auriculata were prepared and antimicrobial activity of these extracts was evaluated against pure cultures of Streptococcus mutans and Enterococcus faecalis using well diffusion and minimum inhibitory concentration (MIC) assays.
Result: The present study results shows an excellent antimicrobial activity of Cassia auriculata of both aqueous and ethanolic extract at 25 to 50 µg/l against e fecalsis and streptococcus mutans. The plant derived synthetic chemical compound can be used for various dental applications like mouthwash, root canal irrigants, toothpaste and dental cements.
Conclusion: Both aqueous and ethanolic extracts show potent antimicrobial activity against Streptococcus mutans and Enterococcus faecalis. Thus this can be applied in the field of medicine and future research can be focussed on various dental applications for orodental care.
Keywords: Cassia auriculata, antimicrobial activity, Streptococcus mutans, Enterococcus faecalis, phytochemicals, medicinal plants, dental caries, endodontic pathogens, molecular docking, ADMET profiling, Good Health and Well-being.
How to cite this article: Mohamed A, Ramesh R. Antimicrobial Evaluation of Cassia Auriculata Extracts Against Streptococcus Mutans and Enterococcus Faecalis: An In Vitro Study. Int J Drug Deliv Technol. 2026;16(8s): 1011-1021; DOI: 10.25258/ijddt.16.8s.114
Source of support: Nil.
Conflict of interest: None