International Journal of Drug Delivery Technology
Volume 16, Issue 8s, 2026

Effect of Hybrid Assistive Neuromuscular Dynamic Therapy and Constraint Induced Movement Therapy in the Upper Extremity Functions in Hemiparetic Patients

1 Anubha Aranake, 2 Dr. Suraj Kanase

1MPT, Department of Neuro Physiotherapy, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Karad.

2Professor / Head of Department of Neuro Physiotherapy, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth, Karad.

Corresponding Author: Dr. Suraj B Kanase, Professor/HOD, Department of Neurophysiotherapy, KVV, Karad
Email: drsurajkanase7@gmail.com

Abstract

Purpose: Stroke is a leading cause of long term disability in adults, often resulting in weakness or paralysis on one side of the body, known as hemiparesis. Upper limb hemiparesis significantly limits a person's ability to perform movements, affecting overall independence. Recovery of arm and hand function is typically slower. While various rehabilitation methods aim to improve motor function, many individuals continue to experience persistent difficulties due to limited movement control, spasticity and reduced sensory feedback. Innovative approaches are needed to enhance motor recovery and support functional independence in stroke survivors.

Materials and methods: A total of 28 participants with post-stroke hemiparesis were randomly assigned into two groups: Group A (control group) received only Constraint Induced Movement Therapy, while Group B (experiment group) received both Hybrid Assistive Neuromuscular Dynamic Therapy and Constraint Induced Movement Therapy. Outcome measures included the Fugl-Meyer Hand Assessment, Action Research Arm Test (ARAT), and Stroke Rehabilitation Assessment of Movement (STREAM), evaluated at baseline (Day1), 2nd week, 4th week, 6th week.

Results: Both groups showed significant improvements over six weeks (p < 0.05), but Group B had greater gains. Group A improved modestly across all the functions measures, while Group B showed larger increases in Fugl-Meyer, ARAT, and STREAM scores (p < 0.0001). Between group analysis confirmed significantly better outcomes in Group B, supporting the effectiveness of constraint induced movement therapy combined with hybrid assistive neuromuscular dynamic therapy.

Conclusion: The combination of Hybrid Assistive Neuromuscular Dynamic Therapy with Constraint Induced Movement Therapy is more effective than Constraint Induced Movement Therapy alone in improving upper extremity function in hemiparetic stroke patients. This dual approach reduces spasticity, enhances neuroplasticity and promotes greater task performance, suggesting that integrating assistive neuromuscular technologies into conventional therapy can significantly advance stroke rehabilitation outcomes.

Keywords: Stroke Rehabilitation, Hemiparesis, Constraint Induced Movement Therapy, Hybrid Assistive Neuromuscular Dynamic Therapy, Upper extremity recovery, Neuroplasticity.

How to cite this article: Aranake A, Kanase S. Effect of Hybrid Assistive Neuromuscular Dynamic Therapy and Constraint Induced Movement Therapy in the Upper Extremity Functions in Hemiparetic Patients. Int J Drug Deliv Technol. 2026;16(8s): 1022-1029; DOI: 10.25258/ijddt.16.8s.115

Source of support: Nil.

Conflict of interest: None