International Journal of Drug Delivery Technology
Volume 16, Issue 8s, 2026

Association of Pregnancy-Related Anxiety With Perceived Social Support: A Cross-Sectional Study Among Third-Trimester Antenatal Women

Dr. S.A. Bavatharini1, Prof. Dr. Vijayalakshmi K2

1Post Graduate, Department of Obstetrics and Gynaecology, Chettinad Hospital and Research Institute, India

2Professor, Department of Obstetrics and Gynaecology, Chettinad Hospital and Research Institute, India


ABSTRACT

Background: Pregnancy-related anxiety (PRA) is common in late gestation and may influence maternal well-being and perinatal outcomes. Perceived social support is a potentially modifiable protective factor, yet clinic-based data among third-trimester antenatal women remain limited. This study (illustrative example) assessed the prevalence of PRA and examined its association with perceived social support among third-trimester women attending a tertiary care teaching hospital.

Methods: In this cross-sectional study, 100 third-trimester antenatal women (≥28 weeks; ≥18 years) were recruited from Chettinad Hospital and Research Institute using consecutive sampling. Women with active or prior psychiatric disorders, active suicidal ideation, major high-risk obstetric complications, substance use disorder, active labor, or cognitive impairment were excluded. Anxiety was measured using the Perinatal Anxiety Screening Scale (PASS) and pregnancy-specific anxiety using the Pregnancy Anxiety Questionnaire–Revised 2 (PRAQ-R2). Perceived social support was assessed using the Multidimensional Scale for Perceived Social Support (MSPSS). Correlation and regression analyses were used to evaluate associations.

Results: The prevalence of clinically significant perinatal anxiety (PASS ≥26) was 38.0%. PASS severity was minimal (0–20) in 46.0%, mild–moderate (21–41) in 41.0%, and severe (42–93) in 13.0%. Mean (SD) MSPSS total score was 59.2 (11.6), with highest perceived support from family. PASS scores showed an inverse association with MSPSS (r = −0.46, p <0.001). In multivariable logistic regression, each 10-point decrease in MSPSS was associated with higher odds of PASS ≥26 (adjusted OR 1.78, 95% CI 1.19–2.66), after controlling for parity, unplanned pregnancy, and family type.

Conclusion: In this illustrative cross-sectional model, pregnancy-related anxiety was common in third trimester and was inversely associated with perceived social support. Integrating brief screening with structured support-oriented counseling may help identify and reduce anxiety burden during routine antenatal care.

Keywords: pregnancy-related anxiety; PASS; PRAQ-R2; MSPSS; perceived social support; third trimester; antenatal; cross-sectional.

How to cite this article: Bavatharini SA, Vijayalakshmi K. Association of Pregnancy-Related Anxiety With Perceived Social Support: A Cross-Sectional Study Among Third-Trimester Antenatal Women. Int J Drug Deliv Technol. 2026;16(8s): 204-209; DOI: 10.25258/ijddt.16.8s.31

Source of support: None

Conflict of interest: None