Assessing Prognostic Accuracy of BISAP versus Ranson's Score in Acute Pancreatitis: An Observational Study

Dr. Shazia Rizvi^*, Dr. Vijay Kanase

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ABSTRACT

Background: The study evaluated the performance of Bed Side Index for Severity of Acute Pancreatitis (BISAP) and Ranson's scores in predicting severity and clinical outcomes (organ failure, ICU admission, mortality) in patients with acute pancreatitis.

Methods: A study was conducted on 96 patients with acute pancreatitis. BISAP scores were calculated within 24 hr of admission while Ranson's scores were assessed on admission and at 48 hr.

Results: Alcohol (50%) and gallstones (31%) were the most common etiologies. At admission, 78% of patients had Ranson scores 0-2 while 24% showed progression at 48 hr. The organ failure rates increased progressively with increasing BISAP scores [9% in scores 0-1, 21% in score 2, and 50% in scores ≥ 3 (p< 0.001)] and with Ranson's scores [2% in scores 0–2, 21% in 3–5, and 100% in ≥ 6 (p< 0.001)]. The patients with a BISAP score ≥3 had a 50% ICU admission, and all patients with a Ranson's score ≥6 needed ICU care. BISAP ≥3 was associated with 25% mortality, while deaths occurred in patients with Ranson ≥6 (p = 1.9 × 10⁻¹¹). The length of hospital stay and readmission rates increased with severity of acute pancreatitis (p< 0.001).

Conclusions: BISAP score effectively identified severe cases, ICU need, and mortality risk within the first 24 hr. Although a Ranson score ≥6 showed perfect specificity, its sensitivity was comparatively lower. Ranson's score showed strong predictive power for mortality but relied on 48-hr data, thus limiting its use for immediate decision making.

Keywords: Acute pancreatitis, BISAP, Organ failure, Ranson.

How to cite this article: Rizvi S, Kanase V. Assessing Prognostic Accuracy of BISAP versus Ranson's Score in Acute Pancreatitis: An Observational Study. Int J Drug Deliv Technol. 2026;16(8s): 232-238; DOI: 10.25258/ijddt.16.8s.34

Source of support: None

Conflict of interest: None