International Journal of Drug Delivery Technology
Volume 16, Issue 9s, 2026

Exploring the Efficacy of Orthokeratology in Myopia Control: A Longitudinal Study in Pediatric Optometry

Dr. Rakibul Hasan Khan (PHD-HC)1, Smita Das2, Ireen Mirza3, Priyom Wary4, Gitismita Devi5, Geetanjali Dutta6

1Program Coordinator & Assistant Professor, Department of Optometry, University of Science & Technology Meghalaya. Email: rakibulhasankhan1988@gmail.com

2Assistant Professor, Department of Optometry, The Assam Royal Global University. Email: smita.asn@gmail.com

3Assistant Professor, Department of Optometry, University of Science & Technology Meghalaya. Email: ireenmirza55@gmail.com

4Assistant Professor, Department of Optometry, University of Science & Technology Meghalaya. Email: ireenmirza55@gmail.com

5Assistant Professor, Department of Optometry, Faculty of Paramedical Sciences, Assam Down Town University, Assam, India. Email: leejadevi11@gmail.com

6Assistant Professor, Department of Optometry, Faculty of Paramedical Sciences, Assam Down Town University, Assam, India. Email: geetanjalidutta0@gmail.com


ABSTRACT

Background: This longitudinal study in pediatric optometry delves into the effectiveness of orthokeratology (Ortho-K) to control myopia in children. The research focuses on unilateral myopic children by comparing the eyes treated with Ortho-K lenses to their emmetropic contralateral counterparts.

Methods: The study entailed a detailed review of 1,568 medical records of kids who had received Ortho-K prescriptions. The investigation was primarily focused on a particular subgroup of 64 kids in this dataset who had received monocular Ortho-K treatment for a period longer than a year. The main result compares the axial lengths of eyes treated with Ortho-K and their emmetropic counterparts. The terms "intra-bilateral absolute reduction in AL growth" (ibARAL) and "intra-bilateral relative reduction in AL growth" (ibRRAL) refer to measures used in the context of assessing changes in axial length growth within both eyes. The research also investigates potential factors influencing these outcomes, such as age, gender, and ocular characteristics. The study investigates the relationships between AL elongation, ibARAL, and ibRRAL using correlation analysis and generalized estimating equation (GEE) analysis.

Results: The results show that monocular orthokeratology (Ortho-K) treatment efficiently inhibits the expansion of the axial length in unilateral myopic eyes.

Keywords: Orthokeratology, Myopia control, Longitudinal study, Pediatric optometry, Efficacy assessment

How to cite this article: Khan R H, Das S, Mirza I, Wary P, Devi G, Dutta G, Exploring the Efficacy of Orthokeratology in Myopia Control: A Longitudinal Study in Pediatric Optometry. Int J Drug Deliv Technol. 2026;16(9s): 781-788; Doi: 10.25258/Ijddt.16.9s.80.

Source of support: Nil

Conflict of interest: None