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In conclusion, this integrated computational approach streamlines the identification of potential HER2 inhibitors, offering a systematic strategy for drug discovery. Eriodictyol emerges as a promising candidate, demonstrating a favorable safety profile and pharmacokinetic attributes, paving the way for further in-depth studies and development as a potential therapeutic agent for breast cancer.
8. Repurposing FDA-Approved Anastrozole-based Drugs for Breast Cancer through Drug-Drug Transcriptomic Similarity and Cavity Detection guided Blind Docking
Tabjez Mujawar, Harshal Tare, Nitin Deshmukh, Babaso Udugade, Ujjwala Thube
23. Potential of Nitrofurantoin Cyclodextrin Nanosponge Complex to Enhance Solubility and Masking Bitter Taste
Adil Khan, Jaiprakash N Sangshetti, Kamran Mukarram
24. Formulation and In-vivo Assessment of Topical Polyherbal Hair Serum to Promote Hair Growth
Himani Singh, M A Naidu
32. Development and Evaluation of Emulgel Formulation of Diclofenac Sodium utilizing Lipidium sativum as a Gelling Agent
Minal Sonule, Sachinkumar D Gunjal, Prasanthi Samathoti, Badmanaban. R, Bharath Raj K C
35. Solubility Enhancement and Formulation Development of an Oral Film of Ondansetron Hydrochloride Monohydrate using Mix-solvency Concept
Kirti Tomer, Saurav Kumar, Swapnil Goyal, Akanksha Dwivedi, Rakhi Khabiya, Sumeet Dwivedi
36. Preparation, Characterization and In-vitro Evaluation of Nano Encapsulated 1-Octacosanol for Solubility Enhancing by using Various Polymers through Spray Drying Approach
A K Singh, R Kharb, J B Kandpal
37. Solubility Enhancement of Poorly Water-Soluble Drug Ritonavir using Polyvinylpyrrolidone and Chitosan-based Platform Technique
Khakal Nilima N, Aloorkar Nagesh H
38. Optimization of the Photodegradation of Metoclopramide Drug using Super Nanoparticles in Aqueous Solutions
Wesam AL H Alhaidry, Farah Aloraibi, Jasim M Abbas, Hawraa AZ Alhussein, Ruaa Sattar
39. Enhanced Solubility and Dissolution Rate of Aceclofenac using Freeze Drying Technique
Vikrant Nikam, Sachin Somwanshi, Vivekanand Kashid, Kiran Kotade, Shubham Shete, Kapil Patil
40. Formulation Development and Evaluation of Highly Oxidative Degradative Drug Molecule Injectable Dosage form by Lyophilisation Techniques
Hitesh Bhakre, Ashish Agrawal, Vivekanand K Chatap
41. Chronopharmacokinetic and Metabolite Studies of the Cardiovascular Medication Sacubitril
Arvind Umarkar, Subhranshu Panda, Hemant Suryavanshi
42. Exploring the Antioxidant Potential of Cissus woodrowii (Stapf Ex Cooke) Santapau: A Study on Leaves and Stem
Pallavi N Patil, Santosh K Singh, Kiran A Wadkar
43. Chronopharmacokinetic and Metabolites Investigations of the Cardiovascular Drugs Perindopril
Arvind Umarkar, Subhranshu Panda, Hemant Suryavanshi
44. Investigation of Antimicrobial Activity and Characterization of Isolated Allyl Isothiocyanate
Prashant B Patil, Hardik Goswami, Arjun Chaudhari, Jayvadan K Patel
45. Pre-clinical and In-silico Analysis of the Augmentation of Dermal Regeneration by Punica granatum Linn Fruit Peel in Rats
Nimmy Varghese, Prerana Shetty, Srusha Samani, Harsha Ashtekar
46. P Glycoprotein Mediated Drug Interaction between Digoxin and Orange Juice- Exploratory Study by In-vitro Approach
Deepalakshmi M, Anslin Joanna, Keerthana Venkat, Malwyn Mofhy, Arun K P
47. Design and Discovery of Genistein-based Drugs as a Potential Tyrosine Kinase Inhibitor for Lung Adenocarcinoma through Hybrid In-silico Methods
Vijay Wakale, Ramanlal Kachave, Pranjal Gholap, Kiran Mahajan, Harshal Tare
48. In-silico Design and Development of Multi-Target Agents Targeting Glycogen Synthase Kinase-3 Beta and Vascular Endothelial Growth Factor Receptor 2 for Acute Myeloid Leukemia
Asmita Gaikwad, Nandu Kayande, Harshal Tare, Babaso Udugade, Ramanlal Kachave
49. Designing, Creating, and Assessing a Modified Pulsincap Delivery System for Intestine Targeting of Fluvastatin in Accordance with Circadian Rhythm
M Mahesh, S Jayakumari
50. Formulation of Herbal Topical Dermatological Dosage Form by Quality by Design Approach
Rupali H Tiple, Shamli R Jamane, Deepak S Khobragade, Dharmendra R Mundhada
51. In-vitro Evaluation and Optimization of Sacubitril and Valsartan Floating Tablet using Natural Polymer
Anil K Goyal, Vinesh Kumar
52. Development of Vaginal Tablet of Clotrimazole Prepared by Applying the Concept of Percolatio Threshold
Hardikar S Rajan, Shaikh N M Mustaqeem, Ansari D M Akbar, Peerzade M Yasir
53. Box-Behnken Design for Formulation, Characterization and In-vivo Antidiabetic Activity of Pioglitazone Loaded Nanostructured Lipid Carriers
Modekar SD, Mohale DS, Kochar NI, Chandewar AV
54. In-silico Study of Methyl Beta D-xylopyranoside: A Spectroscopically Screened Small Molecule from Aganosma dichotoma
Sreya Kosanam, Rajeshwari Pasupula
55. Formulation Development of Mucoadhesive Tablets for Treatment of Hypertension using Losartan Potassium
Ghanshyam M Chavan, Jyothirmayee Devineni, Dhruv Dev, Abhay R Shirode, P S Minhas
56. Evaluation of Insulin Loaded Microspheres for Oral Delivery
Rinki Vishwakarma, Harshal Tare
57. Design and Development of Insulin Loaded Microspheres for Oral Delivery
Rinki Vishwakarma, Harshal Tare, Sachin K Jain
58. Extraction and Characterization of Okra and Almond Gum as a Pharmaceutical Aid
SR Chaudhari, UR Dhuppad
59. Isolation of Gum from Tamarind and Fenugreek Plants and Its Evaluation as Pharmaceutical Excipients
SR Chaudhari, UR Dhuppad
60. Design and Discovery of Silmitasertib-based Drugs as a Potential Casein Kinase II Inhibitor for Cholangiocarcinoma through Hybrid In-silico Ligand-Based Virtual Screening with Molecular Docking Method
Pravin Tajane, Nandu Kayande, Avinash Bhosale, Sumit Deore, Harshal Tare
61. Design, Development and Physicochemical Evaluation of Effervescent Tablets of Antihistamine Drug
Vikrant Nikam, Avinash Bhosale
62. Preparation and Evaluation of PLGA-based Nanoparticles
Ram K Choudhary, Kandukuri A Kumar, Srividya Kommineni, Minal Narkhede, Jyothirmayee Devineni
63. Formulation and Evaluation of Mouth Dissolving Tablet of Biperiden HCL for Treatments of Parkinson’s Disease
Mahavir K Sharma, Rupa Singh, Tejas K Patel, Bhavik Jani, Dhairyashri Kher
64. Donepezil and Quercetin Simultaneous Estimation in Rat Plasma Using Developed Bioanalytical HPLC Method: Relevance in Pharmacokinetic Studies
D Sonawane, V Pokharkar
65. Formulation and Evaluation of Gastro Retentive Floating Tablet of Cetirizine Hydrochloride using Linseed Mucilageas Polymer
Manjusha A. Bhange, Mahendra C. Gunde, Shubhada B. Ukey, Pravinkumar B. Suruse
The current study focuses on the formulation of floating tablets using a natural polymer as a binder (Linseed mucilage). However, in-vivo experiments are still needed to establish the efficacy of the manufactured CH floating tablets.
66. Synthesis, Pharmacological Evaluation, and Docking Studies Of Ethyl Coumarilate Derivatives as Potential Anti-bladder Cancer in a Mouse Model
A K Khalaf, O A Omar
67. A Novel Deep Learning Model for Drug-Drug Interactions
Ali K. A. Raheem, Ban N. Dhannoon
68. Therapeutic and Anticancer Properties of Nerium oleander– A Poison as Medicine
Akhila R James, Sakthidasan Jayaprakash
69. Herbal Nano Formulations for Topical Drug Delivery: Prospective for Multiple Skin Disorders
Jyoti Arsude, Machindra Chavan, Sumit Joshi, Shriram Pethakar, Ganesh Dama
70. The Role of Artificial Intelligence in the Pharmaceutical Sector: A Comprehensive Analysis of its Application from the Discovery Phase to Industrial Implementation
Prajwal S Shinde, Ashish Y Pawar, Swati G Talele
71. Molecular and Cellular Expressions in Breast Cancer Responsible for Drug Resistance
Surendra Agrawal, Pravina Gurjar, Deepak Khobragade
Additionally, this study examines the limitations associated with conventional chemotherapy, endocrine therapies, and targeted medicines, while elucidating the mechanisms underlying treatment resistance and proposing potential strategies to overcome it. Emerging therapies like immunotherapies, epigenetic modulators, and new drug delivery methods are looked at to see if they have the potential to get around mechanisms of resistance and improve patient outcomes. This review aims to give clinicians, researchers, and other healthcare workers a full picture of breast cancer’s complex drug resistance mechanisms. By figuring out the molecular complexities and signaling pathways that lead to treatment resistance, we aim to speed up the development of new therapeutic approaches and personalized interventions. This will bring us closer to the long-awaited goal of beating drug resistance and making breast cancer a manageable, treatable condition.
72. Cubosomes: Recent Developments and Applications from a Global Perspective
Rakesh Mishra, Akash Aher, Tanaji Nandgude, Keshav More, Anuja Kolsure
73. Therapeutic Implementation for Hyperpigmentation and Anti-aging: A Cosmeceutical Approach
Jajnadatta Panda, Abhisek Pal, Pritipadma Panda, Archana Panigrahy
74. Unlocking the Potential of In-silico Approaches: Drug Development and Vaccine Design
Priya V Nikam, Sanjay Kumar, Sachinkumar D Gunjal, Mrunalini H Kulkarni, Surya P Singh
75. A Birds Eye View on Solid Lipid Nanoparticles and Applications in Drug Delivery System
Anita H Pagar, Ashish Y Pawar
76. Extrapyramidal Effects of First and Second Generation Antipsychotics: A Review
Sharumathi SM, Bhavatharini S, Rinu MX, Arun KP, Deepalakshmi M
77. Nanogel: Types, Methods of Preparation, Limitation, Evaluation and Application – A Systematic Review
Saloni Srivastava, Supriyo Saha, Vikash Jakhmola
78. Overview of Antihypertensive Transdermal Drug Delivery System
Shital Bidkar, Akshada Tandale, Abhishek Meher, Jayant Bidkar, Ganesh Dama
79. Premedication of Ranitidine and the Action of Hypersensitivity Reactions to Paclitaxel
Harsh K Brahmbhatt, Nidhi Patel, Tejas K Patel, Tantul Sarkar
80. Ethanopharmacological Activities of Mentha arvensis: An Updated Review
Reshu, Avijit Mazumder, Saumya Das
81. Thevetia peruviana: Its Phytochemistry, Traditional and Medicinal Uses, and Pharmacological Activities
V Singh Chauhan, Avijit Mazumder, Shobhini Chandel
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