Drug Eluting Stent: A Promising Drug Delivery System
Rakesh P. Patel1*, Samir Patel1 , Chetan Borkhataria2
1 Department of Pharmaceutics, S. K. Patel College of Pharmaceutical Education and Research, Ganpat Univesity, Kherva 382711 Mehsana, Gujarat, India.
2 Shree H N Shukla Institute of Pharmaceutical Education & Research, Rajkot, Gujarat, India
ABSTRACT Drug eluting stent is a topic of current interest in the design of drug delivery systems. Drug-eluting stents deliver potentially high doses of drugs locally for variable time periods in the area of stent implantation, directed at the potential restenosis site. While this is currently achievable, optimal pharmacological therapy is still evolving. Acknowledging the challenge of examining such a dynamic and flourishing field, our goals in this article were to provide a broad perspective of the development of drug-eluting stent technology, to summarize the available clinical data, and to introduce emerging concepts for the understanding and application of this new device in clinical practice.